ArticleDiagnostics (Basel, Switzerland)2021
Predictors of Loss of Functional Independence in Parkinson's Disease: Results from the COPPADIS Cohort at 2-Year Follow-Up and Comparison with a Control Group.
Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Prognosis in Parkinson's Disease: An Individual Patient Data Meta-Analysis of Six European Incidence Cohorts.Movement disorders : official journal of the Movement Disorder Society · 2026Pooled it
- Medical device-based neuromodulation for motor symptoms in Parkinson's disease: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Combined Effects of Depression, Fatigue and Cardiovascular Dysfunction on Functional Dependence Over Seven Years in Early Parkinson's Disease.Movement disorders clinical practice · 2026Article
- Longitudinal patterns of loss of independence in Parkinson disease.Neurodegenerative disease management · 2026Article
- Characterization of Walking in Mild Parkinson's Disease: Reliability, Validity and Discriminant Ability of the Six-Minute Walk Test Instrumented with a Single Inertial Sensor.Sensors (Basel, Switzerland) · 2024Article
- Tinetti balance performance is associated with mortality in older adults with late-onset Parkinson's disease: a longitudinal study.BMC geriatrics · 2023Observational
- Nomogram to Predict the Probability of Functional Dependence in Early Parkinson's Disease.Journal of Parkinson's disease · 2023Article
- Divergence Between Informant and Self-Ratings of Activities of Daily Living Impairments in Parkinson's Disease.Frontiers in aging neuroscience · 2022Article
- MNCD: A New Tool for Classifying Parkinson's Disease in Daily Clinical Practice.Diagnostics (Basel, Switzerland) · 2021Article
- Fatigue-Related Changes of Daily Function: Most Promising Measures for the Digital Age.Digital biomarkersReview
Corrections and comments
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Authors and funding
50 authors at 20 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveThe aim of this study was to compare the progression of independence in activities of daily living (ADL) in Parkinson's disease (PD) patients versus a control group, as well as to identify predictors of disability progression and functional dependency (FD). PATIENTS AND
methodsPD patients and control subjects, who were recruited from 35 centers of Spain from the COPPADIS cohort between January 2016 and November 2017 (V0), were included. Patients and subjects were then evaluated again at the 2-year follow-up (V2). Disability was assessed with the Schwab & England Activities of Daily Living Scale (S&E-ADLS) at V0 and V2. FD was defined as an S&E-ADLS score less than 80%.
resultsIn the PD group, a significant decrease in the S&E-ADLS score from V0 to V2 (N = 507; from 88.58 ± 10.19 to 84.26 ± 13.38;
conclusionsIn conclusion, autonomy for ADL worsens in PD patients compared to controls. Cognitive impairment, gait problems, fatigue, depressive symptoms, more advanced disease, and a non-tremor phenotype are independent predictors of FD in the short-term.
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