Evidence map›Paper›PMID 34679499›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Rapid Simultaneous Testing of Multiple Antibiotics by the MALDI-TOF MS Direct-on-Target Microdroplet Growth Assay.

Evgeny A Idelevich, Ilka D Nix, Janika A Busch, Katrin Sparbier, Oliver Drews, Markus Kostrzewa, Karsten Becker

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. DOT-MGA for rapid determination of susceptibility to the combination of Ceftazidime-avibactam and Aztreonam among Enterobacterales.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Evgeny A IdelevichFriedrich Loeffler-Institute of Medical Microbiology, University Medicine Greifswald, 17475 Greifswald, Germany.
Ilka D NixInstitute of Medical Microbiology, University Hospital Münster, 48149 Münster, Germany.
Janika A BuschInstitute of Medical Microbiology, University Hospital Münster, 48149 Münster, Germany.
Katrin SparbierBruker Daltonics GmbH & Co. KG, 28359 Bremen, Germany.
Oliver DrewsBruker Daltonics GmbH & Co. KG, 28359 Bremen, Germany.
Markus KostrzewaBruker Daltonics GmbH & Co. KG, 28359 Bremen, Germany.ORCID 0000-0003-0501-6215
Karsten BeckerFriedrich Loeffler-Institute of Medical Microbiology, University Medicine Greifswald, 17475 Greifswald, Germany.ORCID 0000-0002-6391-1341
Bruker (Germany) · DEFriedrich-Loeffler-Institut · DEUniversity Hospital Münster · DE

Funding

European Regional Development Fund GHS-20-0010Federal Ministry of Education and Research 16GW0149KFederal Ministry of Education and Research 16GW0150
6 · The paper itself

Abstract

Accelerating antimicrobial susceptibility testing (AST) is a priority in the development of novel microbiological methods. The MALDI-TOF MS-based direct-on-target microdroplet growth assay (DOT-MGA) has recently been described as a rapid phenotypic AST method. In this proof-of-principle study, we expanded this method to simultaneously test 24 antimicrobials. An

Indexed as

direct-on-target microdroplet growth assayEnterobacteralesMALDI-TOFmultiple antibioticsmultiplex testingrapid susceptibility testing

Identifiers

PMID34679499
PMCPMC8534412
OpenAlexW3204639124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.