Evidence map›Paper›PMID 34679482›Full record

ArticleDiagnostics (Basel, Switzerland)2021

The Comparison and Interpretation of Machine-Learning Models in Post-Stroke Functional Outcome Prediction.

Shih-Chieh Chang, Chan-Lin Chu, Chih-Kuang Chen, Hsiang-Ning Chang, Alice M K Wong, Yueh-Peng Chen, Yu-Cheng Pei

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shih-Chieh ChangDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.
Chan-Lin ChuCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Chih-Kuang ChenCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Hsiang-Ning ChangDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.
Alice M K WongDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Taoyuan, Taoyuan 333, Taiwan.
Yueh-Peng ChenCenter for Artificial Intelligence in Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.
Yu-Cheng PeiDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan.ORCID 0000-0001-5986-0046

Funding

Chang Gung Medical Foundation BMRPB67Chang Gung Medical Foundation CMRPG3J1521-2Chang Gung Medical Foundation CMRPG3K0231-2Chang Gung Medical Foundation CMRPG5H0051-3Chang Gung Memorial Hospital, Linkou CIRPG3H0012Chang Gung Memorial Hospital, Linkou CLRPG3H0012
6 · The paper itself

Abstract

Prediction of post-stroke functional outcomes is crucial for allocating medical resources. In this study, a total of 577 patients were enrolled in the Post-Acute Care-Cerebrovascular Disease (PAC-CVD) program, and 77 predictors were collected at admission. The outcome was whether a patient could achieve a Barthel Index (BI) score of >60 upon discharge. Eight machine-learning (ML) methods were applied, and their results were integrated by stacking method. The area under the curve (AUC) of the eight ML models ranged from 0.83 to 0.887, with random forest, stacking, logistic regression, and support vector machine demonstrating superior performance. The feature importance analysis indicated that the initial Berg Balance Test (BBS-I), initial BI (BI-I), and initial Concise Chinese Aphasia Test (CCAT-I) were the top three predictors of BI scores at discharge. The partial dependence plot (PDP) and individual conditional expectation (ICE) plot indicated that the predictors' ability to predict outcomes was the most pronounced within a specific value range (e.g., BBS-I < 40 and BI-I < 60). BI at discharge could be predicted by information collected at admission with the aid of various ML models, and the PDP and ICE plots indicated that the predictors could predict outcomes at a certain value range.

Indexed as

activities of daily livingfunctional recoverymachine learningpost-acute carerehabilitationstroke

Identifiers

PMID34679482
PMCPMC8534424

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.