ReviewDiagnostics (Basel, Switzerland)2021
The Use of Saliva as a Biosample in the Light of COVID-19.
Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Comparison of the 1 and 2% pilocarpine mouthwash in a xerostomic population: a randomized clinical trial.BMC oral health · 2022Trial
- Association of OPG, TNF-α, and IL-1B Gene Variants With Periodontitis in a South African Population.International dental journal · 2026Observational
- Local and General Inflammatory Mediators Status in Patients with Oral Lichen Planus.Biomedicines · 2026Article
- Determination of objective taste perception among Iranian medical sciences students during COVID‑19 pandemic in Yazd, Eastern Iran: a case-control pilot study.BMC infectious diseases · 2024Article
- Salivary Histamine Levels in Patients with Oral Lichen Planus Lesions.Medicina (Kaunas, Lithuania) · 2024Article
- Assessment of dimensional stability of novel VPES impression material at different time intervals with standard disinfectants.BMC oral health · 2024Article
- Enhancing saliva diagnostics: The impact of amylase depletion on MALDI-ToF MS profiles as applied to COVID-19.Journal of mass spectrometry and advances in the clinical lab · 2024Article
- Two-trace two-dimensional correlation spectra (2T2D-COS) analysis using FTIR spectra to monitor the immune response by COVID-19.Journal of molecular medicine (Berlin, Germany) · 2024Article
- The Importance of Chitosan Coatings in Dentistry.Marine drugs · 2023Review
- The Impact of Competitive Sports on Oral Health: Exploring Their Relationship with Salivary Oxidative Stress in Children.Healthcare (Basel, Switzerland) · 2023Article
- Geographic Variations in Human Mobility Patterns during the First Six Months of the COVID-19 Pandemic in California.Applied sciences (Basel, Switzerland) · 2023Article
- Stress as worsening of the signs and symptoms of the geographic tongue during the COVID-19 pandemic: a pilot study.BMC oral health · 2022Article
- Effects of Various Disinfection Methods on the Material Properties of Silicone Dental Impressions of Different Types and Viscosities.International journal of molecular sciences · 2022Article
- How Did the COVID-19 Pandemic Effect Dental Patients? An Italian Observational Survey Study.Healthcare (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Saliva is easy to collect and a biofluid that is readily available without the need for special equipment for its collection. The collection process, which is non-invasive and inexpensive, leads to obtaining a biomaterial that can serve as a source of information for molecular diagnostics of diseases in general medicine, genetics and dentistry. Unfortunately, many of the salivary methodologies are lacking important parameters to provide for not only the safety of the operator, but also the quality and reproducibility of the research. Since the COVID-19 pandemic, salivary diagnostics demonstrate a great potential for research of SARS-CoV 2. In this review, good practice for unstimulated saliva collection and patient preparation was provided, based on the latest literature and available guidelines. Schemes for saliva collection procedures were presented following an extended literature search. Descriptions of salivary probes/cups, techniques of saliva collection, and the use of specific buffering solutions for the stability of collected samples for SARS-CoV-2 detection were also evaluated.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.