Evidence map›Paper›PMID 34679464›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Evaluation of the Advanta Dx SARS-CoV-2 RT-PCR Assay, a High-Throughput Extraction-Free Diagnostic Test for the Detection of SARS-CoV-2 in Saliva: A Diagnostic Accuracy Study.

Sofia Balaska, Dimitrios Pilalas, Anna Takardaki, Paraskevoula Koutra, Eleftheria Parasidou, Ioanna Gkeka, Areti Tychala, Georgios Meletis, Barbara Fyntanidou, Simeon Metallidis and 2 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Molecular Diagnostic Testing (December 2023).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Guideline
  2. Review
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Sofia BalaskaDepartment of Microbiology, AHEPA University Hospital, Medical School, Aristotle University οf Thessaloniki, 54636 Thessaloniki, Greece.
Dimitrios PilalasFirst Propedeutic Department of Internal Medicine, AHEPA University Hospital, Medical School, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0003-1362-8027
Anna TakardakiDepartment of Microbiology, AHEPA University Hospital, Medical School, Aristotle University οf Thessaloniki, 54636 Thessaloniki, Greece.
Paraskevoula KoutraDepartment of Microbiology, AHEPA University Hospital, Medical School, Aristotle University οf Thessaloniki, 54636 Thessaloniki, Greece.
Eleftheria ParasidouDepartment of Microbiology, AHEPA University Hospital, Medical School, Aristotle University οf Thessaloniki, 54636 Thessaloniki, Greece.
Ioanna GkekaDepartment of Microbiology, AHEPA University Hospital, Medical School, Aristotle University οf Thessaloniki, 54636 Thessaloniki, Greece.
Areti TychalaDepartment of Microbiology, AHEPA University Hospital, Medical School, Aristotle University οf Thessaloniki, 54636 Thessaloniki, Greece.
Georgios MeletisDepartment of Microbiology, AHEPA University Hospital, Medical School, Aristotle University οf Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0001-8750-513X
Barbara FyntanidouEmergency Department, AHEPA University Hospital, 54636 Thessaloniki, Greece.
Simeon MetallidisFirst Department of Internal Medicine, Infectious Diseases Division, AHEPA University Hospital, Medical School, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Efthymia ProtonotariouDepartment of Microbiology, AHEPA University Hospital, Medical School, Aristotle University οf Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0001-8755-1662
Lemonia SkouraDepartment of Microbiology, AHEPA University Hospital, Medical School, Aristotle University οf Thessaloniki, 54636 Thessaloniki, Greece.
Aristotle University of Thessaloniki · GRAHEPA University Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal swab specimen (NPS) molecular testing is considered the gold standard for SARS-CoV-2 detection. However, saliva is an attractive, noninvasive specimen alternative. The aim of the study was to evaluate the diagnostic accuracy of Advanta Dx SARS-CoV-2 RT-PCR saliva-based assay against paired NPS tested with either NeumoDx

Indexed as

COVID-19PCRsalivaSARS-CoV-2

Identifiers

PMID34679464
PMCPMC8534356
OpenAlexW3203125652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.