Evidence map›Paper›PMID 34679439›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Potential Role of Hydroxyapatite Nanocrystalline for Early Diagnostics of Ovarian Cancer.

Ruslana Chyzhma, Artem Piddubnyi, Sergey Danilchenko, Olha Kravtsova, Roman Moskalenko

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 14 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ruslana ChyzhmaDepartment of Pathology, Sumy State University, 40007 Sumy, Ukraine.
Artem PiddubnyiDepartment of Pathology, Sumy State University, 40007 Sumy, Ukraine.ORCID 0000-0002-6508-0131
Sergey DanilchenkoInstitute of Applied Physics NAS of Ukraine, 40007 Sumy, Ukraine.
Olha KravtsovaDepartment of Pathology, Sumy State University, 40007 Sumy, Ukraine.
Roman MoskalenkoDepartment of Pathology, Sumy State University, 40007 Sumy, Ukraine.ORCID 0000-0002-2342-0337
Sumy State University · UAInstitute of Applied Physics · UA

Funding

Ministry of Education and Science of Ukraine No. 0112U100471
6 · The paper itself

Abstract

Calcification is one of the clinical and morphological manifestations of ovarian tumors and it begins at the initial stages of carcinogenesis. Thus, this process can be used for the early diagnostics of some malignant ovarian tumors. We compared the results of ultrasound and histology and found that calcifications of a size less than 200 μm are not detected by ultrasound. These calcified structures are round fragile particles of different sizes. In the EDX (Energy-dispersive X-ray spectroscopy) spectra, the main lines were from Ca and P, and the ratio of these elements corresponds to hydroxyapatite. Thus, we established that hydroxyapatite is the main mineral component of ovarian psammoma bodies and could be used for early diagnostics of ovarian malignant neoplasia.

Indexed as

calcificationearly diagnosticshydroxyapatiteovarian cancer

Identifiers

PMID34679439
PMCPMC8534774
OpenAlexW3201399107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.