Evidence map›Paper›PMID 34679421›Full record

ArticleBrain sciences2021

Functional Connectivity at Rest between the Human Medial Posterior Parietal Cortex and the Primary Motor Cortex Detected by Paired-Pulse Transcranial Magnetic Stimulation.

Rossella Breveglieri, Sara Borgomaneri, Matteo Filippini, Marina De Vitis, Alessia Tessari, Patrizia Fattori

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A Short Route for Reach Planning between Human V6A and the Motor Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rossella BreveglieriDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-5059-1441
Sara BorgomaneriCenter for Studies and Research in Cognitive Neuroscience, University of Bologna, 47521 Cesena, Italy.ORCID 0000-0003-4959-6442
Matteo FilippiniDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Marina De VitisDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Alessia TessariDepartment of Psychology "Renzo Canestrari", University of Bologna, 40127 Bologna, Italy.ORCID 0000-0002-6616-2454
Patrizia FattoriDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
University of Bologna · ITFondazione Santa Lucia · IT

Funding

European Union MAIA-951910
6 · The paper itself

Abstract

The medial posterior parietal cortex (PPC) is involved in the complex processes of visuomotor integration. Its connections to the dorsal premotor cortex, which in turn is connected to the primary motor cortex (M1), complete the fronto-parietal network that supports important cognitive functions in the planning and execution of goal-oriented movements. In this study, we wanted to investigate the time-course of the functional connectivity at rest between the medial PPC and the M1 using dual-site transcranial magnetic stimulation in healthy humans. We stimulated the left M1 using a suprathreshold test stimulus to elicit motor-evoked potentials in the hand, and a subthreshold conditioning stimulus was applied over the left medial PPC at different inter-stimulus intervals (ISIs). The conditioning stimulus affected the M1 excitability depending on the ISI, with inhibition at longer ISIs (12 and 15 ms). We suggest that these modulations may reflect the activation of different parieto-frontal pathways, with long latency inhibitions likely recruiting polisynaptic pathways, presumably through anterolateral PPC.

Indexed as

functional connectivitymedial posterior parietal cortexpaired pulse stimulationparieto-M1 networktranscranial magnetic stimulation

Identifiers

PMID34679421
PMCPMC8534070
OpenAlexW3206967019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.