Evidence map›Paper›PMID 34679370›Full record

ArticleBrain sciences2021

The Potential Impact of Digital Biomarkers in Multiple Sclerosis in The Netherlands: An Early Health Technology Assessment of MS Sherpa.

Sonja Cloosterman, Inez Wijnands, Simone Huygens, Valérie Wester, Ka-Hoo Lam, Eva Strijbis, Bram den Teuling, Matthijs Versteegh

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Health Technology Assessment in the Early Phases of Development of Medical Devices: A Catalyst for Sustainable Growth and Innovation.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025
    Article
  5. Article
  6. Advances in Neurodegenerative Diseases.Journal of clinical medicine · 2023
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sonja CloostermanOrikami Digital Health Products, Ridderstraat 29, 6511 TM Nijmegen, The Netherlands.
Inez WijnandsOrikami Digital Health Products, Ridderstraat 29, 6511 TM Nijmegen, The Netherlands.
Simone HuygensInstitute for Medical Technology Assessment (iMTA), Erasmus University of Rotterdam, Burgemeester Oudlaan 50, 3062 PA Rotterdam, The Netherlands.
Valérie WesterInstitute for Medical Technology Assessment (iMTA), Erasmus University of Rotterdam, Burgemeester Oudlaan 50, 3062 PA Rotterdam, The Netherlands.ORCID 0000-0002-2691-7162
Ka-Hoo LamDepartment of Neurology, MS Center Amsterdam, Amsterdam University Medical Centers, Location VUmc, De Boelelaan, 1117 HV Amsterdam, The Netherlands.
Eva StrijbisDepartment of Neurology, MS Center Amsterdam, Amsterdam University Medical Centers, Location VUmc, De Boelelaan, 1117 HV Amsterdam, The Netherlands.
Bram den TeulingOrikami Digital Health Products, Ridderstraat 29, 6511 TM Nijmegen, The Netherlands.
Matthijs VersteeghInstitute for Medical Technology Assessment (iMTA), Erasmus University of Rotterdam, Burgemeester Oudlaan 50, 3062 PA Rotterdam, The Netherlands.
Amsterdam University Medical Centers · NLErasmus University Rotterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1)

Indexed as

AIdigital biomarkersdigital healthdigital therapeuticsdisease modellingearly detection(early) Health Technology AssessmenteHealthhome monitoringMS disease activityMS disease progressionmultiple sclerosis

Identifiers

PMID34679370
PMCPMC8534078
OpenAlexW3204163491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.