Cortical Visual Impairment in Childhood: 'Blindsight' and the Sprague Effect Revisited.

Gerry Leisman, Calixto Machado, Robert Melillo

Open access · goldAbstract readReview

In one paragraph

Review in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.1field-weighted citation impact, top 57% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

Exploring rare mitochondrial DNA in Leber hereditary optic neuropathy.Advances in ophthalmology practice and research
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Gerry LeismanMovement and Cognition Laboratory, Department of Physical Therapy, University of Haifa, Haifa 3498838, Israel.ORCID 0000-0002-9975-7331

Calixto MachadoInstitute of Neurology and Neurosurgery, Havana 10400, Cuba.ORCID 0000-0002-0539-5844

Robert MelilloMovement and Cognition Laboratory, Department of Physical Therapy, University of Haifa, Haifa 3498838, Israel.

Instituto de Neurologia Y Neurocirugia · CUUniversidad de Ciencias Médicas de la Habana · CUUniversity of Haifa · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The paper discusses and provides support for diverse processes of brain plasticity in visual function after damage in infancy and childhood in comparison with injury that occurs in the adult brain. We provide support and description of neuroplastic mechanisms in childhood that do not seemingly exist in the same way in the adult brain. Examples include the ability to foster the development of thalamocortical connectivities that can circumvent the lesion and reach their cortical destination in the occipital cortex as the developing brain is more efficient in building new connections. Supporting this claim is the fact that in those with central visual field defects we can note that the extrastriatal visual connectivities are greater when a lesion occurs earlier in life as opposed to in the neurologically mature adult. The result is a significantly more optimized system of visual and spatial exploration within the 'blind' field of view. The discussion is provided within the context of "blindsight" and the "Sprague Effect".

Indexed as

blindsightcortical blindnesscortical visual impairmentinfant visionSprague Effectvision

Identifiers

PMID34679344

DOI10.3390/brainsci11101279

PMCPMC8533908

OpenAlexW3202698873

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.