Evidence map›Paper›PMID 34679343›Full record

ArticleBrain sciences2021

Symptoms of Autism Spectrum Disorder in Individuals with Down Syndrome.

Amanda Dimachkie Nunnally, Vivian Nguyen, Claudine Anglo, Audra Sterling, Jamie Edgin, Stephanie Sherman, Elizabeth Berry-Kravis, Laura Del Hoyo Soriano, Leonard Abbeduto, Angela John Thurman

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Alternative Diagnoses in the Work Up of Down Syndrome Regression Disorder.Journal of autism and developmental disorders · 2025
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Toward Equity in Research on Intellectual and Developmental Disabilities.American journal on intellectual and developmental disabilities · 2023
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Amanda Dimachkie NunnallyMIND Institute, University of California Davis Health, 2825 50th Street, Sacramento, CA 95816, USA.ORCID 0000-0001-6272-9882
Vivian NguyenMIND Institute, University of California Davis Health, 2825 50th Street, Sacramento, CA 95816, USA.
Claudine AngloMIND Institute, University of California Davis Health, 2825 50th Street, Sacramento, CA 95816, USA.
Audra SterlingWaisman Center and Department of Communication Sciences and Disorders, University of Wisconsin-Madison, Madison, WI 53706, USA.
Jamie EdginDepartment of Psychology, University of Arizona, Tucson, AZ 85721, USA.
Stephanie ShermanDepartment of Human Genetics, School of Medicine, Emory University, Atlanta, GA 30322, USA.
Elizabeth Berry-KravisDepartments of Pediatrics, Neurological Sciences and Biochemistry, Rush University Medical Center, Chicago, IL 60612, USA.
Laura Del Hoyo SorianoMIND Institute, University of California Davis Health, 2825 50th Street, Sacramento, CA 95816, USA.
Leonard AbbedutoMIND Institute, University of California Davis Health, 2825 50th Street, Sacramento, CA 95816, USA.ORCID 0000-0002-2311-7194
Angela John ThurmanMIND Institute, University of California Davis Health, 2825 50th Street, Sacramento, CA 95816, USA.
University of California, Davis · USEmory University · USRush University Medical Center · USUniversity of Arizona · USUniversity of Wisconsin–Madison · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JUDY A. VAN DE WATER · 2020 to 2026
$9.7M
Expressive Language Sampling as an Outcome MeasureR01HD074346 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ABBEDUTO, LEONARD J. · 2013 to 2017
$3.9M
NCATS NIH HHS UL1 TR001860NICHD NIH HHS P50 HD103526NICHD NIH HHS R01 HD074346NIH HHS P50HD103526NIH HHS R01HD074346NIH HHS UL1TR001860
6 · The paper itself

Abstract

There is a growing body of evidence to suggest that individuals with Down syndrome (DS) are diagnosed with autism spectrum disorders (ASD) at a higher rate than individuals in the general population. Nonetheless, little is known regarding the unique presentation of ASD symptoms in DS. The current study aims to explore the prevalence and profiles of ASD symptoms in a sample of individuals with DS (

Indexed as

autism spectrum disorderco-occurringDown syndromeprevalence

Identifiers

PMID34679343
PMCPMC8533848
OpenAlexW3203187647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.