Evidence map›Paper›PMID 34679324›Full record

ReviewBrain sciences2021

The Genetics of Sleep Disorders in Children: A Narrative Review.

Greta Mainieri, Angelica Montini, Antonio Nicotera, Gabriella Di Rosa, Federica Provini, Giuseppe Loddo

Abstract readReview
In one paragraph

Review in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Greta MainieriDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-6159-854X
Angelica MontiniDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40138 Bologna, Italy.
Antonio NicoteraUnit of Child Neurology and Psychiatry, Department of Human Pathology of the Adult and Developmental Age, "Gaetano Barresi" University of Messina, 98124 Messina, Italy.
Gabriella Di RosaUnit of Child Neurology and Psychiatry, Department of Human Pathology of the Adult and Developmental Age, "Gaetano Barresi" University of Messina, 98124 Messina, Italy.
Federica ProviniDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40138 Bologna, Italy.
Giuseppe LoddoAzienda USL di Bologna, 40124 Bologna, Italy.ORCID 0000-0001-8748-5984

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep is a universal, highly preserved process, essential for human and animal life, whose complete functions are yet to be unravelled. Familial recurrence is acknowledged for some sleep disorders, but definite data are lacking for many of them. Genetic studies on sleep disorders have progressed from twin and family studies to candidate gene approaches to culminate in genome-wide association studies (GWAS). Several works disclosed that sleep-wake characteristics, in addition to electroencephalographic (EEG) sleep patterns, have a certain degree of heritability. Notwithstanding, it is rare for sleep disorders to be attributed to single gene defects because of the complexity of the brain network/pathways involved. Besides, the advancing insights in epigenetic gene-environment interactions add further complexity to understanding the genetic control of sleep and its disorders. This narrative review explores the current genetic knowledge in sleep disorders in children, following the International Classification of Sleep Disorders-Third Edition (ICSD-3) categorisation.

Indexed as

circadian rhythm sleep-wake disordershypersomnolenceinsomniaparasomniassleep-related breathing disorderssleep-related movement disorders

Identifiers

PMID34679324
PMCPMC8534132

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.