ArticlePloS one2021
Racial and ethnic differences in foveal avascular zone in diabetic and nondiabetic eyes revealed by optical coherence tomography angiography.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Individualized FAZ morphometry and standardized peri-FAZ vascular density: a pilot AngioVue OCTA study in diabetic retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Influence of Refraction on Widefield Retinal and Choroidal Vascular Metrics in Optical Coherence Tomography Angiography in a Caucasian Population.Translational vision science & technology · 2026Article
- Diagnostic value of ocular imaging biomarkers in chronic obstructive pulmonary disease: a multicenter prospective cross-sectional study.Journal of thoracic disease · 2026Article
- Smaller Optic Discs Show Higher Macular Flow Density: An Optical Coherence Tomography Angiography Study.Biomedicines · 2026Article
- Diabetes May Modulate the Association Between Age and Optical Coherence Tomography Angiography Parameters: A Serial, Cross-Sectional Study.Journal of personalized medicine · 2026Article
- Automated FAZ segmentation and diabetic retinopathy classification using OCTA images.BMC ophthalmology · 2025Article
- Inverted internal limiting membrane flap technique for full-thickness macular holes in Black Africans.International ophthalmology · 2025Article
- What do You Need to Know after Diabetes and before Diabetic Retinopathy?Aging and disease · 2025Review
- Association between free triiodothyronine and diabetic retinopathy: insights from a longitudinal cohort study and Mendelian randomization.Frontiers in endocrinology · 2025Article
- Intravitreal aflibercept for diabetic macular edema: structural and functional improvements.Frontiers in medicine · 2025Article
- Comparing Optical Coherence Tomography Angiography Metrics in Healthy Chinese and Caucasian Adults.Journal of personalized medicine · 2024Article
- Pathoanatomical aspects of macular hole closure: Emerging concepts.Indian journal of ophthalmology · 2024Article
- Assessing the Sensitivity of OCT-A Retinal Vasculature Metrics.Translational vision science & technology · 2023Article
- A normative database of wide-field swept-source optical coherence tomography angiography quantitative metrics in a large cohort of healthy adults.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- Impact of inter-ethnic anatomical findings on current surgical outcome, established biomarkers, and future artificial intelligence algorithms.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Racial differences in quantitative optical coherence tomography angiography findings between older non-diabetics with co-morbidities.PloS one · 2023Article
- Quantitative Volumetric Analysis of Retinal Ischemia with an Oxygen Diffusion Model and OCT Angiography.Ophthalmology scienceArticle
- Macular Sublayer Thickness in Healthy Iranian Children: An Optical Coherence Tomography Study from the Population-Based Shiraz Pediatric Eye Study.Journal of current ophthalmologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeThe purpose of this study was to examine whether racial and ethnic differences in retinal microvasculature are detectable with quantitative measures derived from optical coherence tomography angiography (OCTA).
methodsOCTA scans and fundus photography were obtained in 447 eyes from 271 patients with and without diabetes between April and October 2018. Fundus photos were graded by the hospital reading center for diabetic retinopathy (DR) severity. Eight OCTA parameters relating to the foveal avascular zone (FAZ), superficial vascular perfusion, and deep vascular perfusion were analyzed for significant differences between race and ethnicity groups, self-reported by patients and organized according to National Center for Health Statistics groupings. Multiple regression was then used to adjust estimates for possible confounding by age, gender, hypertension, and last hemoglobin A1c level.
resultsSignificant differences in FAZ area were found between white and non-white patients. After adjustment, the differences between white and all non-white groups were statistically significant (p<0.05) among patients with mild to moderate DR. In those without diabetes, the Hispanic and Asian groups had significantly larger FAZ areas (p<0.005) than NH white patients. In those with mild to moderate non-proliferative diabetic retinopathy (NPDR), NH Black, Hispanic, and Asian patients also had significantly larger FAZ areas than NH white patients (p<0.005).
conclusionSignificant differences in FAZ area exist among different racial and ethnic groups. These results highlight the importance of considering and further studying race and ethnicity in OCTA analyses of the retinal microvasculature.
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