Trial reportPloS one2021
Healthcare worker stress, anxiety and burnout during the COVID-19 pandemic in Singapore: A 6-month multi-centre prospective study.
Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed, 4 syntheses or guidelines pooled it, 219 citations in OpenAlex.
- Workplace Mental Health Programs for Healthcare Workers: A Systematic Review.International journal of environmental research and public health · 2026Pooled it
- Organizational interventions to support and promote the mental health of healthcare workers during pandemics and epidemics: a systematic review.BMC health services research · 2025Pooled it
- The Prevalence and Determinants of Mental Health Problems in Lebanon: A Meta-Analytic Study of 3957 Healthcare Workers.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2025Pooled it
- A global overview of healthcare workers' turnover intention amid COVID-19 pandemic: a systematic review with future directions.Human resources for health · 2022Pooled it
- Building a resilient oncology workforce in the Asia-Pacific: From outcomes to systems thinking in workforce well-being.Asia-Pacific journal of oncology nursing · 2026Article
- Digital Health Monitoring and Intervention Suite for Stress in Frontline Nurses: Prospective Cohort Trial.JMIR formative research · 2026Article
- Article
- Occupational Hazards, Social Support, and Quality of Working Life in Sub-District Health Promoting Hospitals in Southern Thailand: A Cross-Sectional Study.International journal of environmental research and public health · 2026Article
- Impact of COVID-19 on early identification of protein-energy malnutrition in the cancer care setting: a repeated cross-sectional survey of cancer care professionals.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Mentally active versus passive sedentary behaviors and burnout among nurses of China: a cross-sectional study.Frontiers in public health · 2026Article
- Observational
- Prevalence and predictors of stress, anxiety, and depression among healthcare workers during the COVID-19 pandemic at a mental referral hospital in Kampala, Uganda.BMC public health · 2025Article
- Toward Digital Self-Monitoring of Mental Health in the General Population: Scoping Review of Existing Approaches to Self-Report Measurement.JMIR mental health · 2025Article
- Career stage variations in mental and somatic health symptoms among nursing professionals in China: a cross-sectional study.BMC nursing · 2025Article
- Exploring the use of mindfulness for prevention of burnout in allied health professionals in Singapore.Work (Reading, Mass.) · 2025Article
- [Mental distress of intensive care staff in Germany during the COVID-19 pandemic. Results from the VOICE study].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Article
- Impact of a standardized quality care model on anxiety in patients retained in the emergency department: A retrospective study.Medicine · 2025Article
- Impact of Receiving Coronavirus Disease 2019 (COVID-19) Vaccination on Work Stress of Healthcare Workers: A Cross-Sectional Study.Journal of acute medicine · 2025Article
- Article
- Predictors of stress among nucleic acid sampling support nurses (NASSNs) during the COVID-19 pandemic.Human resources for health · 2025Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe long-term stress, anxiety and job burnout experienced by healthcare workers (HCWs) are important to consider as the novel coronavirus disease (COVID-19) pandemic stresses healthcare systems globally. The primary objective was to examine the changes in the proportion of HCWs reporting stress, anxiety, and job burnout over six months during the peak of the pandemic in Singapore. The secondary objective was to examine the extent that objective job characteristics, HCW-perceived job factors, and HCW personal resources were associated with stress, anxiety, and job burnout.
methodA sample of HCWs (doctors, nurses, allied health professionals, administrative and operations staff; N = 2744) was recruited via invitation to participate in an online survey from four tertiary hospitals. Data were gathered between March-August 2020, which included a 2-month lockdown period. HCWs completed monthly web-based self-reported assessments of stress (Perceived Stress Scale-4), anxiety (Generalized Anxiety Disorder-7), and job burnout (Physician Work Life Scale).
resultsThe majority of the sample consisted of female HCWs (81%) and nurses (60%). Using random-intercept logistic regression models, elevated perceived stress, anxiety and job burnout were reported by 33%, 13%, and 24% of the overall sample at baseline respectively. The proportion of HCWs reporting stress and job burnout increased by approximately 1·0% and 1·2% respectively per month. Anxiety did not significantly increase. Working long hours was associated with higher odds, while teamwork and feeling appreciated at work were associated with lower odds, of stress, anxiety, and job burnout.
conclusionsPerceived stress and job burnout showed a mild increase over six months, even after exiting the lockdown. Teamwork and feeling appreciated at work were protective and are targets for developing organizational interventions to mitigate expected poor outcomes among frontline HCWs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.