Expression, Purification and Refolding of a Human Na

Ryan V Schroder, Leah S Cohen, Ping Wang, Joekeem D Arizala, Sébastien F Poget

Abstract read

In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryan V SchroderDepartment of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA.

Leah S CohenDepartment of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA.

Ping WangDepartment of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA.

Joekeem D ArizalaDepartment of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA.ORCID 0000-0003-4406-5597

Sébastien F PogetDepartment of Chemistry, College of Staten Island, University of New York, 2800 Victory Blvd., Staten Island, NY 10314, USA.ORCID 0000-0003-1724-3386

Funding

Elucidation of structural details of binding and activity in sodium channel gating-modifier toxinsR15GM124606 · NIGMS · COLLEGE OF STATEN ISLAND · PI POGET, SEBASTIEN F · 2017 to 2017

$454k

NIGMS NIH HHS R15 GM124606NIH HHS 1R15GM124606

6 · The paper itself

Abstract

The voltage-gated sodium channel Na

Indexed as

Protein FoldingAmino Acid SubstitutionBinding SitesEscherichia coliHumansNAV1.7 Voltage-Gated Sodium ChannelRecombinant ProteinsSpider VenomsNAV1.7 Voltage-Gated Sodium ChannelRecombinant ProteinsSpider Venomsbacterial expression of mammalian proteinslipid reconstitutionmembrane protein refoldingpeptide toxinvoltage-gated sodium channelvoltage sensor

Identifiers

PMID34679015

DOI10.3390/toxins13100722

PMCPMC8541342

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.