Evidence map›Paper›PMID 34678965›Full record

ReviewToxics2021

The Effects of Essential and Non-Essential Metal Toxicity in the

Mitchell R Slobodian, Jesse D Petahtegoose, Athena L Wallis, Danica C Levesque, Thomas J S Merritt

Abstract readReview
In one paragraph

Review in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Effects of ZnFeToxics · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mitchell R SlobodianFaculty of Science and Engineering, Laurentian University, 935 Ramsey Lake Rd, Sudbury, ON P3E 2C6, Canada.ORCID 0000-0002-1644-8278
Jesse D PetahtegooseFaculty of Science and Engineering, Laurentian University, 935 Ramsey Lake Rd, Sudbury, ON P3E 2C6, Canada.
Athena L WallisFaculty of Science and Engineering, Laurentian University, 935 Ramsey Lake Rd, Sudbury, ON P3E 2C6, Canada.
Danica C LevesqueFaculty of Science and Engineering, Laurentian University, 935 Ramsey Lake Rd, Sudbury, ON P3E 2C6, Canada.ORCID 0000-0001-8745-3827
Thomas J S MerrittFaculty of Science and Engineering, Laurentian University, 935 Ramsey Lake Rd, Sudbury, ON P3E 2C6, Canada.ORCID 0000-0002-4795-7534

Funding

Natural Sciences and Engineering Research Council RGPIN-2018-05551
6 · The paper itself

Abstract

The biological effects of environmental metal contamination are important issues in an industrialized, resource-dependent world. Different metals have different roles in biology and can be classified as essential if they are required by a living organism (e.g., as cofactors), or as non-essential metals if they are not. While essential metal ions have been well studied in many eukaryotic species, less is known about the effects of non-essential metals, even though essential and non-essential metals are often chemically similar and can bind to the same biological ligands. Insects are often exposed to a variety of contaminated environments and associated essential and non-essential metal toxicity, but many questions regarding their response to toxicity remain unanswered.

Indexed as

copper homeostasisDrosophila melanogasteressential metalsiron homeostasismetallothioneinsmetal toxicitymetal transcription factornon-essential metalszinc homeostasis

Identifiers

PMID34678965
PMCPMC8540122

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.