ArticleToxics2021
Association between Blood Mercury Concentration and Prevalence of Borderline Hypercholesterolemia among Adolescents: The Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2013 and 2016.
Article in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- The Association Between Blood Mercury and Lipid Biomarkers in US Hypertensive Adults.Biological trace element research · 2024Article
- Metal mixture exposures and serum lipid levels in childhood: the Rhea mother-child cohort in Greece.Journal of exposure science & environmental epidemiology · 2024Article
- Association of Blood Total Mercury with Dyslipidemia in a sample of U.S. Adolescents: Results from the National Health and Nutrition Examination Survey Database, 2011-2018.Hygiene and environmental health advances · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is limited evidence on the association between blood mercury (Hg) concentration and the risk of borderline dyslipidemia in adolescents. Here, we investigated the association between blood Hg concentration and the prevalence of borderline dyslipidemia among Korean adolescents. A total of 1559 participants (806 boys and 753 girls) aged 10-18 years who cross-sectionally enrolled in the Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2013 and 2016 were included in this study. Hg concentrations (µg/L) in whole blood samples were measured. The geometric mean (GM) of the blood Hg concentration was 1.88 µg/L. It showed a 63% higher prevalence of borderline hypercholesterolemia (total cholesterol (TC) 170-199 mg/dL) per unit of natural log-transformed blood Hg concentration in boys (95% CI = 1.10-2.41), but not in girls. When a categorical model was applied, the positive association with the prevalence of borderline hypercholesterolemia was also persistant in boys (OR (95% CI) for 2nd and 3rd tertiles (Hg concentration 1.532-11.761 µg/L) vs. 1st tertile (Hg concentration 0.192-1.531 µg/L): 1.92 (1.19-3.10)), but not in girls. This finding suggests that blood Hg concentration might result in a higher prevalence of borderline hypercholesterolemia among adolescents and more stringent public health actions should be taken for the reduction of Hg exposure to prevent dyslipidemia from early-childhood, despite the need of further study to evaluate a causal relationship between blood Hg concentration and the risk of dyslipidemia.
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