ArticleMedicine2021
Polypharmacy and potentially inappropriate medications among elderly patients in the geriatric department at a single-center in China: A retrospective cross-sectional study.
Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Cardiovascular risk associated with polypharmacy in heart failure: a systematic review and meta-analysis.ESC heart failure · 2026Pooled it
- Potentially inappropriate medications in older outpatients with depression: a cross-sectional study comparing the Beers criteria and the Chinese criteria.Frontiers in psychiatry · 2026Article
- A Scoping Review on the Prevalence of Potentially Inappropriate Medication and Polypharmacy among Older People in a Lower-middle Income Country.JMA journal · 2025Review
- Understanding polypharmacy for people receiving home care services: a scoping review of the evidence.Age and ageing · 2025Article
- Association between polypharmacy and 2-year outcomes among Chinese older inpatients: a multi-center cohort study.BMC geriatrics · 2024Article
- Association between number of medications and indicators of potentially inappropriate polypharmacy: a population-based cohort of older adults in Quebec, Canada.Therapeutic advances in drug safety · 2024Article
- The Attitudes Toward Polypharmacy and Willingness to Deprescribe Among Patients with Multimorbidity in Rural Areas of Shandong Province in China: A Cross-Sectional Study.Patient preference and adherence · 2024Article
- Polypharmacy and potentially inappropriate medicine use in older adults with cancer: a multicenter cross-sectional study in Northwest Ethiopia oncologic centers.Journal of pharmaceutical policy and practice · 2024Article
- Prevalence and clinical implications of polypharmacy and potentially inappropriate medication in elderly patients with heart failure: results of six months' follow-up.Journal of geriatric cardiology : JGC · 2023Article
- Multimorbidity and polypharmacy in hospitalized older patients: a cross-sectional study.BMC geriatrics · 2023Article
- The Impact of Potentially Inappropriate Medications and Polypharmacy on 3-Month Hospital Readmission among Older Patients: A Retrospective Cohort Study from Malaysia.Geriatrics (Basel, Switzerland) · 2023Article
- Evaluation of potentially inappropriate medications for the elderly according to beers, STOPP, START, and Chinese criteria.Frontiers in pharmacology · 2023Article
- Attitudes of Older Adult Patients and Caregivers Towards Deprescribing of Medications in Ethiopia.Clinical interventions in aging · 2023Article
- Pharmacotherapy Problems in Best Possible Medication History of Hospital Admission in the Elderly.Pharmacy (Basel, Switzerland) · 2022Article
- Potentially Inappropriate Medications among Elderly with Frailty in a Tertiary Care Academic Medical Centre in Saudi Arabia.Healthcare (Basel, Switzerland) · 2022Article
- Risk prediction model of polypharmacy for community-dwelling elderly patients: An assessment tool for early detection.Frontiers in pharmacology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
abstractThe aging of the population has become a worldwide concern, especially in China. Polypharmacy and potentially inappropriate medications (PIMs) are prominent issues in elderly patients. Therefore, the aim of this study was to investigate the prevalence of polypharmacy and PIMs in older inpatients and further to explore the factors associated with PIM use.A retrospective, single-center, cross-sectional study was conducted. A total of 1200 inpatients aged 65 years or older admitted from January 2015 to December 2015 were included. The prevalence of polypharmacy (5-9 medications) and hyperpolypharmacy (10 or more medications) was calculated. The 2019 American Geriatric Society Beers criteria were applied to assess PIMs use. Multivariate logistic regression was used to determine the independent factors of PIM use, while zero-inflated negative binomial regression was performed to evaluate the relationship between polypharmacy and PIM use.The median age of the study population was 76 years (interquartile range = 71-81). The median number of medications was 9 (interquartile range = 7-12). 91.58% of the patients took 5 or more medications simultaneously, and 30.08% of the patients were subjected to one or more PIMs. Spironolactone, furosemide, and zopiclone were the top 3 most frequently encountered PIMs. Hyperpolypharmacy and older age were identified as independent factors associated with PIM use. The risk of PIMs rises with the number of medications prescribed.Polypharmacy and PIM use were common in our study, and the risk of PIM use correlated with an increase in the number of medications already prescribed.
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