Evidence map›Paper›PMID 34678068›Full record

ArticleScience advances2021

Motor training improves coordination and anxiety in symptomatic

Yuanlei Yue, Pan Xu, Zhichao Liu, Xiaoqian Sun, Juntao Su, Hongfei Du, Lingling Chen, Ryan T Ash, Stelios Smirnakis, Rahul Simha and 3 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Modulating alternative splicing ofScience translational medicine · 2026
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  10. Review
  11. Evidence-based complementary and alternative medicine : eCAM · 2023
    Article
  12. Article
  13. Article
  14. Using deep learning to study emotional behavior in rodent models.Frontiers in behavioral neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Yuanlei YueDepartment of Pharmacology and Physiology, School of Medicine and Health Sciences, The George Washington University, Washington, DC 20037, USA.ORCID 0000-0002-0552-2911
Pan XuDepartment of Pharmacology and Physiology, School of Medicine and Health Sciences, The George Washington University, Washington, DC 20037, USA.ORCID 0000-0001-9324-1513
Zhichao LiuDepartment of Physics, Columbian College of Arts and Sciences, The George Washington University, Washington, DC 20037, USA.ORCID 0000-0002-9274-7229
Xiaoqian SunDepartment of Computer Science, School of Engineering and Applied Science, The George Washington University, Washington, DC 20037, USA.
Juntao SuDepartment of Statistics, Columbian College of Arts and Sciences, The George Washington University, Washington, DC 20037, USA.
Hongfei DuDepartment of Statistics, Columbian College of Arts and Sciences, The George Washington University, Washington, DC 20037, USA.ORCID 0000-0002-0633-594X
Lingling ChenDepartment of Pharmacology and Physiology, School of Medicine and Health Sciences, The George Washington University, Washington, DC 20037, USA.
Ryan T AshDepartment of Psychiatry, Stanford University, Palo Alto, CA 94305, USA.
Stelios SmirnakisDepartment of Neurology, Brigham and Women's Hospital, Jamaica Plain VA Hospital, Harvard Medical School, Boston, MA 02115, USA.
Rahul SimhaDepartment of Computer Science, School of Engineering and Applied Science, The George Washington University, Washington, DC 20037, USA.ORCID 0000-0002-0689-9411
Linda KusnerDepartment of Pharmacology and Physiology, School of Medicine and Health Sciences, The George Washington University, Washington, DC 20037, USA.ORCID 0000-0002-5530-2140
Chen ZengDepartment of Physics, Columbian College of Arts and Sciences, The George Washington University, Washington, DC 20037, USA.ORCID 0000-0001-7778-6388
Hui LuDepartment of Pharmacology and Physiology, School of Medicine and Health Sciences, The George Washington University, Washington, DC 20037, USA.ORCID 0000-0003-2336-2170
George Washington University · USBrigham and Women's Hospital · USPalo Alto University · US

Funding

Mechanisms and rescue of neural circuit dysfunction in Mecp2 mutant miceR00NS089824 · NINDS · GEORGE WASHINGTON UNIVERSITY · PI LU, HUI · 2017 to 2019
$747k
M1 circuit dysfunction in MECP2 duplication syndromeR21NS096640 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI SMIRNAKIS, STELIOS MANOLIS · 2016 to 2017
$500k
NINDS NIH HHS R00 NS089824NINDS NIH HHS R21 NS096640
6 · The paper itself

Abstract

Rett syndrome (RTT) is a severe neurodevelopmental disorder caused by loss of function of the X-linked methyl-CpG–binding protein 2 (

Identifiers

PMID34678068
PMCPMC8535852
OpenAlexW3205929781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.