Evidence map›Paper›PMID 34677818›Full record

ReviewStem cell reviews and reports2022

Investigating Adult Stem Cells Through Lineage analyses.

Daniel Kalderon

Abstract readReview
In one paragraph

Review in Stem cell reviews and reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Daniel KalderonDepartment of Biological Sciences, Columbia University, 1212 Amsterdam Avenue, New York, NY, 10027, USA. ddk1@columbia.edu.ORCID 0000-0002-2149-0673

Funding

Somatic stem cells in the Drosophila ovaryR01GM079351 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DANIEL D KALDERON · 2009 to 2026
$5.8M
NIGMS NIH HHS R01 GM079351
6 · The paper itself

Abstract

A simple, universal and fundamental definition of adult stem cell communities is proposed. Key principles of cell lineage methods for defining adult stem cell numbers, locations and behaviors are critically evaluated, emphasizing the imperatives of capturing the full spectrum of individual stem cell behaviors, examining a variety of experimental time periods and avoiding unwarranted assumptions. The focus is first on defining fundamentals and then addresses stem cell heterogeneity, potential hierarchies and how individual cells serve the function of a stem cell community.

Indexed as

Adult Stem CellsCell LineageStem CellsAdult stem cellDivision-independent differentiationDrosophila ovarian follicle stem cellsDynamic heterogeneityLineage analysisMouse epidermal stem cellsMouse gut stem cellsPopulation asymmetry

Identifiers

PMID34677818
PMCPMC8799514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.