Evidence map›Paper›PMID 34677805›Full record

ArticleJournal of nephrology2022

Comparison of 30-day case-fatality rate between dialysis and transplant Covid-19 patients: a propensity score matched cohort study.

Tainá Veras de Sandes-Freitas, Luís Gustavo Modelli de Andrade, Lucio Roberto Requião Moura, Marina Pontello Cristelli, José Osmar Medina-Pestana, Jocemir Ronaldo Lugon, Ricardo Sesso, Brazilian Covid-19 Dialysis Investigators and the Covid-19-KT Brazilian Study Group

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 94 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Tainá Veras de Sandes-Freitas *Programa de Pós-Graduação Em Ciências Médicas, Departamento de Medicina Clínica, Faculdade de Medicina, Universidade Federal Do Ceará, Fortaleza, CE, Brazil.ORCID http://orcid.org/0000-0002-4435-0614
Luís Gustavo Modelli de Andrade *Departamento de Medicina Interna, Universidade Estadual Paulista-UNESP, Botucatu, SP, Brazil.ORCID http://orcid.org/0000-0002-0230-0766
Lucio Roberto Requião MouraHospital Do Rim, Fundação Oswaldo Ramos, São Paulo, SP, Brazil. lucio.requiao@gmail.com.ORCID http://orcid.org/0000-0001-8751-9048
Marina Pontello CristelliHospital Do Rim, Fundação Oswaldo Ramos, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-2813-0400
José Osmar Medina-PestanaHospital Do Rim, Fundação Oswaldo Ramos, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-0750-7360
Jocemir Ronaldo Lugon *Departamento de Medicina, Divisão de Nefrologia, Universidade Federal Fluminense, Rio de Janeiro, RJ, Brazil.ORCID http://orcid.org/0000-0001-6791-3910
Ricardo Sesso *Departamento de Medicina, Disciplina de Nefrologia, Universidade Federal de São Paulo. Rua Botucatu, 740, São Paulo, SP, 04023-062, Brazil.ORCID http://orcid.org/0000-0002-1062-0073
Brazilian Covid-19 Dialysis Investigators and the Covid-19-KT Brazilian Study Group
Hospital do Rim e Hipertensão · BRHospital Israelita Albert Einstein · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Ceará · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesPatients undergoing kidney replacement therapies (KRTs) have a poor prognosis after Covid-19 infection. Few studies have compared the outcomes of such patients in the different KRT modalities. This study aimed to analyze the 30-day Covid-19-associated case-fatality rate of dialysis and kidney transplant patients.

methodsRetrospective cohort study analyzing data from patients with confirmed Covid-19 between Mar/20 and Jan/21 included in two multicenter studies, the Brazilian Covid-19 Dialysis Study (Dialysis group, n = 703) and the Covid-19-KT Brazilian Study (Transplant group, n = 1907). To assess the risk factors for death, adjusted Cox hazards models were used. A sensitivity analysis was performed using a propensity score analysis to match the groups (n = 587 patients in each group).

resultsA higher percentage of transplant patients required hospitalization (68 vs. 51%, p < 0.001), intensive care (37 vs. 30%, p = 0.023), and invasive mechanical ventilation (28 vs. 22%, p = 0.035). Multivariate analysis of the before-matching sample showed that subjects in the transplant group were at a lower death risk at baseline (HR

conclusionBoth transplant and dialysis patients have high 30-day case-fatality rates after a Covid-19 diagnosis. Despite lower death risk at baseline, transplant patients have an increased death risk of 6% per day than dialysis patients.

Indexed as

COVID-19COVID-19 TestingCohort StudiesHumansPropensity ScoreRenal DialysisRetrospective StudiesSARS-CoV-2COVID-19Kidney transplantationPropensity scoreRenal dialysis

Identifiers

PMID34677805
PMCPMC8532104
OpenAlexW3206697305

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.