Evidence map›Paper›PMID 34677802›Full record

ArticleIndian journal of pediatrics2022

Screening for COVID-19 in Children Undergoing Elective Invasive Procedures.

Briseida López-Martinez, Gerardo Blanco-Rodríguez, Israel Parra-Ortega, Cesar Emmanuel Ramirez-Martinez, Miguel Angel Villasis-Keever, Maria Guadalupe Miranda-Novales, Miguel Klünder-Klünder, Daniela De la Rosa Zamboni, Monica Villa Guillen, Jaime Nieto-Zermeño and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Indian journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Briseida López-MartinezAuxiliary Diagnostic Services, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico.
Gerardo Blanco-RodríguezThoracic Surgery and Endoscopy Service, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico.
Israel Parra-OrtegaAuxiliary Diagnostic Services, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico.
Cesar Emmanuel Ramirez-MartinezThoracic Surgery and Endoscopy Service, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico.
Miguel Angel Villasis-KeeverAnalysis and Synthesis of the Evidence Research Unit, National Medical Center XXI Century, Instituto Mexicano del Seguro Social, Mexico City, México.
Maria Guadalupe Miranda-NovalesAnalysis and Synthesis of the Evidence Research Unit, National Medical Center XXI Century, Instituto Mexicano del Seguro Social, Mexico City, México.
Miguel Klünder-KlünderMedical Research Direction, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico.
Daniela De la Rosa ZamboniEpidemiology Services, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico.
Monica Villa GuillenMedical Director, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico.
Jaime Nieto-ZermeñoMedical Director, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico.
Juan Garduño-EspinosaHospital Director, Hospital Infantil de México Federico Gómez, Ministry of Health (SSA), Mexico City, Mexico.
Jessie Nallely Zurita-CruzFacultad de Medicina, Universidad Nacional Autónoma de México, Hospital Infantil de México Federico Gómez, Mexico City, 06720, Mexico. zuritajn@hotmail.com.
Hospital Infantil de México Federico Gómez · MXMexican Social Security Institute · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report the frequency of asymptomatic infection with SARS-CoV-2 in pediatric patients undergoing invasive medical procedures in a tertiary pediatric hospital.

methodsFrom June to October 2020, a SARS-CoV-2 real-time reverse-transcription polymerase chain reaction (rRT-PCR) test was performed for all pediatric patients scheduled to undergo an elective invasive procedure. None of the patients was symptomatic. The cycle threshold (Ct) values of the ORF1ab gene were recorded for all patients.

resultsA total of 700 patients were screened for SARS-CoV-2 infection. The median age was 5.7 y old. In total, 46.6% (n = 326) of the patients were male, and 53.4% (n = 374) were female. The most common underlying diseases were hemato-oncological (25.3%), gastrointestinal (24.9%), and genitourinary (10.3%). The main scheduled surgical-medical procedures were surgical treatment for acquired congenital diseases, biopsy sampling, local therapy administration, organ transplantation, and the placement of central venous catheters, among others. The SARS-CoV-2 rRT-PCR test was positive in 9.4% (66), and the median Ct value was 35.8. None of the patients developed COVID-19.

conclusionsThe frequency of asymptomatic SARS-CoV-2 infection was detected in less than 10% of pediatric patients scheduled to undergo an elective invasive procedure in a tertiary hospital. This frequency is higher than those in reports from different countries.

Indexed as

COVID-19Asymptomatic InfectionsChildChild, PreschoolFemaleHumansMaleMass ScreeningReal-Time Polymerase Chain ReactionSARS-CoV-2AsymptomaticChildrenCOVID-19SARS-CoV-2

Identifiers

PMID34677802
PMCPMC8531893
OpenAlexW3205560058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.