Evidence map›Paper›PMID 34677682›Full record

ReviewEuropean child & adolescent psychiatry2023

The management of ADHD in children and adolescents: bringing evidence to the clinic: perspective from the European ADHD Guidelines Group (EAGG).

David Coghill, Tobias Banaschewski, Samuele Cortese, Philip Asherson, Daniel Brandeis, Jan Buitelaar, David Daley, Marina Danckaerts, Ralf W Dittmann, Manfred Doepfner and 11 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European child & adolescent psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

David Coghill *Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia.
Tobias Banaschewski *Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.
Samuele CorteseCentre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
Philip AshersonSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Daniel BrandeisChild and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.
Jan BuitelaarDepartment of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
David DaleyDivision of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, UK.
Marina DanckaertsResearch Group of Developmental Psychiatry, Center for Developmental Psychiatry, KU Leuven, Kapucijnenvoer 7, Blok H, 3000, Leuven, Belgium.
Ralf W DittmannPaediatric Psychopharmacology, Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.
Manfred DoepfnerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine, University Hospital Cologne, University of Cologne, Cologne, Germany.
Maite FerrinHaringey CAMHS, NHS, and ReCognition Health, London, UK.
Chris HollisDivision of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, UK.
Martin HoltmannLWL-University Hospital for Child and Adolescent Psychiatry, Ruhr-University Bochum, Hamm, Germany.
Santosh ParamalaDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Edmund Sonuga-BarkeDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
César SoutulloLouis A Fallace Department of Psychiatry and Behavioral Science, University of Texas, Houston, TX, USA.
Hans-Christoph SteinhausenDepartment of Child and Adolescent Psychiatry, Aarhus University, Aarhus, Denmark.
Saskia Van der OordClinical Psychology, KU Leuven, Leuven, Belgium.
Ian C K WongSchool of Pharmacy, University College London, London, UK.
Alessandro ZuddasChild and Adolescent Neuropsychiatry Unit, Department of Biomedical Sciences, University of Cagliari and Antonio Cao Paediatric Hospital, G. Brotzu Hospital Trust, Cagliari, Italy.
Emily SimonoffLWL-University Hospital for Child and Adolescent Psychiatry, Ruhr-University Bochum, Hamm, Germany. emily.simonoff@kcl.ac.uk.ORCID http://orcid.org/0000-0002-5450-0823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ADHD is the most common neurodevelopmental disorder presenting to child and adolescent mental health, paediatric, and primary care services. Timely and effective interventions to address core ADHD symptoms and co-occurring problems are a high priority for healthcare and society more widely. While much research has reported on the benefits and adverse effects of different interventions for ADHD, these individual research reports and the reviews, meta-analyses and guidelines summarizing their findings are sometimes inconsistent and difficult to interpret. We have summarized the current evidence and identified several methodological issues and gaps in the current evidence that we believe are important for clinicians to consider when evaluating the evidence and making treatment decisions. These include understanding potential impact of bias such as inadequate blinding and selection bias on study outcomes; the relative lack of high-quality data comparing different treatments and assessing long-term effectiveness, adverse effects and safety for both pharmacological and non-pharmacological treatments; and the problems associated with observational studies, including those based on large national registries and comparing treatments with each other. We highlight key similarities across current international clinical guidelines and discuss the reasons for divergence where these occur. We discuss the integration of these different perspective into a framework for person/family-centered evidence-based practice approach to care that aims to achieve optimal outcomes that prioritize individual strengths and impairments, as well as the personal treatment targets of children and their families. Finally, we consider how access to care for this common and impairing disorder can be improved in different healthcare systems.

Indexed as

Attention Deficit Disorder with HyperactivityAdolescentAmbulatory Care FacilitiesChildHumansMental HealthAttention deficit hyperactivity disorderEvidence-based medicineGuidelineIntervention

Identifiers

PMID34677682
PMCPMC8532460

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.