Evidence map›Paper›PMID 34677662›Full record

Observational studyEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2022

Role of bacterial colonisation of vancomycin-gentamicin spacers in two-stage arthroplasty revision surgery: the usefulness of spacer sonication.

Sandra Huguet, Martí Bernaus, Lucía Gómez, Eva Cuchí, Alex Soriano, Lluís Font-Vizcarra

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sandra HuguetDepartment of Traumatology and Orthopaedics, Hospital Universitari Mútua Terrassa, Barcelona, Spain. sanhumi@gmail.com.ORCID http://orcid.org/0000-0001-8540-3834
Martí BernausDepartment of Traumatology and Orthopaedics, Hospital Universitari Mútua Terrassa, Barcelona, Spain.
Lucía GómezOsteoarticular Infections Unit, Hospital Universitari Mútua Terrassa, Barcelona, Spain.
Eva CuchíOsteoarticular Infections Unit, Hospital Universitari Mútua Terrassa, Barcelona, Spain.
Alex SorianoDepartment of Infectious Diseases - Osteoarticular Infections Unit, Hospital Clínic, Barcelona, Spain.
Lluís Font-VizcarraDepartment of Traumatology and Orthopaedics, Hospital Universitari Mútua Terrassa, Barcelona, Spain.
Mútua Terrassa · ESHospital Clínic de Barcelona · ESHospital de Viladecans · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn two-stage replacements for septic loosening, some studies have suggested an association between bacterial colonisation of spacers and a higher number of complications after implantation of the definitive prosthesis. Our study aimed to determine the reoperation rate of patients undergoing two-stage revision surgery according to the culture results of spacer sonication.

methodsA retrospective observational study was conducted in which hip or knee spacers implanted at our institution with a diagnosis of periprosthetic joint infection from 2010 to 2018 were analysed. Patients were grouped into three categories: A. Patients with positive spacer sonication fluid culture, with or without positive cultures of the rest of the samples. B. Patients with negative spacer sonication culture and negative cultures of the rest of intraoperative samples. C. Patients with negative spacer sonication culture but positive cultures of the rest of intraoperative samples.

resultsA total of 45 spacers were analysed: 10 were included in group A, 24 in group B and 11 in group C. The reoperation rate during the first year after the 2-stage revision surgery was 20%, 29.2% and 54.5% for each group, respectively, due to an infection in 10%, 20.8% and 45.5%. Spacers were colonised in all cases by low virulent micro-organisms.

conclusionIn our study, bacterial colonisation of the spacer is not associated with a higher rate of reoperation. The group of patients with positive intraoperative cultures during the second-stage had the highest reoperation rate.

Indexed as

Arthroplasty, Replacement, HipProsthesis-Related InfectionsAnti-Bacterial AgentsGentamicinsHumansReoperationSonicationVancomycinAnti-Bacterial AgentsGentamicinsVancomycinPeriprosthetic joint infectionRevision surgerySonicationSpacerTwo-stage surgery

Identifiers

PMID34677662
OpenAlexW3207807315

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.