Evidence map›Paper›PMID 34677471›Full record

ReviewMarine drugs2021

Research Progress in Anti-Inflammatory Bioactive Substances Derived from Marine Microorganisms, Sponges, Algae, and Corals.

Chao-Qun Li, Qin-Yuan Ma, Xiu-Zhen Gao, Xuan Wang, Bei-Li Zhang

Abstract readReview
In one paragraph

Review in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
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  13. The Plethora of Microbes with Anti-Inflammatory Activities.International journal of molecular sciences · 2024
    Review
  14. Green (Journal of immunology research · 2024
    Article
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chao-Qun LiSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.
Qin-Yuan MaSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.
Xiu-Zhen GaoSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.ORCID 0000-0002-9162-0509
Xuan WangKey Laboratory of Mariculture (Ministry of Education), Fisheries College, Ocean University of China, Qingdao 266003, China.
Bei-Li ZhangSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.

Funding

Natural Science Foundation of Shandong Province ZR2020MC053
6 · The paper itself

Abstract

Inflammation is the body's defense reaction in response to stimulations and is the basis of various physiological and pathological processes. However, chronic inflammation is undesirable and closely related to the occurrence and development of diseases. The ocean gives birth to unique and diverse bioactive substances, which have gained special attention and been a focus for anti-inflammatory drug development. So far, numerous promising bioactive substances have been obtained from various marine organisms such as marine bacteria and fungi, sponges, algae, and coral. This review covers 71 bioactive substances described during 2015-2020, including the structures (65 of which), species sources, evaluation models and anti-inflammatory activities of these substances. This review aims to provide some reference for the research progress of marine-organism-derived anti-inflammatory metabolites and give more research impetus for their conversion to novel anti-inflammatory drugs.

Indexed as

Aquatic OrganismsBiological ProductsAnimalsAnthozoaAnti-Inflammatory AgentsHumansInflammationMicroalgaePoriferaResearchAnti-Inflammatory AgentsBiological Productsanti-inflammatory activitycoralinflammatory pathwaysmarine algaemarine bacteria and funginatural productsponge

Identifiers

PMID34677471
PMCPMC8538560

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.