Evidence map›Paper›PMID 34677456›Full record

ArticleMarine drugs2021

Evaluation of the Effects of Fucoidans from

Philipp Dörschmann, Sarah Apitz, Inga Hellige, Sandesh Neupane, Susanne Alban, Georg Kopplin, Signe Ptak, Xavier Fretté, Johann Roider, Marietta Zille and 1 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Fucoidan fromMarine drugs · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Effects of Fucoidans on Activated Retinal Microglia.International journal of molecular sciences · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Arctic Edible Brown AlgaPlants (Basel, Switzerland) · 2023
    Article
  15. Comparison of Fucoidans fromInternational journal of molecular sciences · 2023
    Article
  16. Interaction of High-Molecular Weight Fucoidan fromInternational journal of molecular sciences · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Philipp DörschmannDepartment of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.
Sarah ApitzDepartment of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.
Inga HelligeFraunhofer Research and Development Center for Marine and Cellular Biotechnology EMB, Mönkhofer Weg 239a, 23562 Lübeck, Germany.
Sandesh NeupanePharmaceutical Institute, Kiel University, Gutenbergstraße 76, 24118 Kiel, Germany.
Susanne AlbanPharmaceutical Institute, Kiel University, Gutenbergstraße 76, 24118 Kiel, Germany.
Georg KopplinAlginor ASA, Haraldsgata 162, 5525 Haugesund, Norway.ORCID 0000-0002-5167-9848
Signe PtakDepartment of Chemical Engineering, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.ORCID 0000-0003-1993-3751
Xavier FrettéDepartment of Chemical Engineering, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.ORCID 0000-0001-5002-1465
Johann RoiderDepartment of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.
Marietta ZilleFraunhofer Research and Development Center for Marine and Cellular Biotechnology EMB, Mönkhofer Weg 239a, 23562 Lübeck, Germany.
Alexa KlettnerDepartment of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.
Christian-Albrechts-Universität zu Kiel · DEUniversity of Southern Denmark · DKFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering · DEUniversity of Vienna · AT

Funding

Interreg 39-1.0-16
6 · The paper itself

Abstract

Fucoidans are algal polysaccharides that exhibit protective properties against oxidative stress. The aim of this study was to investigate different fucoidans from brown seaweeds for their ability to protect against iron-dependent oxidative stress (ferroptosis), a main hallmark of retinal and brain diseases, including hemorrhage. We investigated five new high-molecular weight fucoidan extracts from

Indexed as

FucusLaminariaAntioxidantsAquatic OrganismsCell DeathCell LineHumansHydrogen PeroxideIronNeuronsOxidative StressPolysaccharidesRetinaAntioxidantsfucoidanHydrogen PeroxideIronPolysaccharidesalgaeF. distichus subsp. evanescensferroptosisF. serratusF. vesiculosushemorrhageneuronsretinal pigment epitheliumseaweeduveal melanoma

Identifiers

PMID34677456
PMCPMC8538076
OpenAlexW3201830637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.