Evidence map›Paper›PMID 34677455›Full record

ArticleMarine drugs2021

Synthesis and Characterization of 2-Decenoic Acid Modified Chitosan for Infection Prevention and Tissue Engineering.

Carlos Montez Wells, Emily Carol Coleman, Rabeta Yeasmin, Zoe Lynn Harrison, Mallesh Kurakula, Daniel L Baker, Joel David Bumgardner, Tomoko Fujiwara, Jessica Amber Jennings

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Carlos Montez WellsDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0003-4835-7503
Emily Carol ColemanDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, USA.
Rabeta YeasminDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, USA.
Zoe Lynn HarrisonDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, USA.
Mallesh KurakulaDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0002-8130-7068
Daniel L BakerDepartment of Chemistry, The University of Memphis, Memphis, TN 38152, USA.
Joel David BumgardnerDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0002-7467-3078
Tomoko FujiwaraDepartment of Chemistry, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0002-3329-0361
Jessica Amber JenningsDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, USA.ORCID 0000-0002-2760-6948
University of Memphis · US

Funding

National Science Foundation 194509
6 · The paper itself

Abstract

Chitosan nanofiber membranes are recognized as functional antimicrobial materials, as they can effectively provide a barrier that guides tissue growth and supports healing. Methods to stabilize nanofibers in aqueous solutions include acylation with fatty acids. Modification with fatty acids that also have antimicrobial and biofilm-resistant properties may be particularly beneficial in tissue regeneration applications. This study investigated the ability to customize the fatty acid attachment by acyl chlorides to include antimicrobial 2-decenoic acid. Synthesis of 2-decenoyl chloride was followed by acylation of electrospun chitosan membranes in pyridine. Physicochemical properties were characterized through scanning electron microscopy, FTIR, contact angle, and thermogravimetric analysis. The ability of membranes to resist biofilm formation by

Indexed as

AnimalsAnti-Bacterial AgentsBandagesBiocompatible MaterialsBiofilmsChitosanFatty Acids, MonounsaturatedHumansMiceNIH 3T3 CellsPseudomonas aeruginosaStaphylococcus aureusStructure-Activity RelationshipTissue EngineeringWound Healing2-decenoic acidAnti-Bacterial AgentsBiocompatible MaterialsChitosanFatty Acids, Monounsaturatedacylationantimicrobialbiomaterialschitosanelectrospunlocal delivery

Identifiers

PMID34677455
PMCPMC8538315
OpenAlexW3204048844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.