Evidence map›Paper›PMID 34677412›Full record

ArticleMetabolites2021

Metabolomic Profile of Young Adults Born Preterm.

Serafina Perrone, Simona Negro, Elisa Laschi, Marco Calderisi, Maurizio Giordano, Giuseppe De Bernardo, Gianni Parigi, Anna Laura Toni, Susanna Esposito, Giuseppe Buonocore

Abstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Oxidative Stress in Fetuses and Newborns.Antioxidants (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Urine and FecalMetabolites · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Serafina PerroneDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-5478-5657
Simona NegroMaternity and Childhood Department, Neonatal Intensive Care, University Hospital of Siena, 53100 Siena, Italy.ORCID 0000-0003-4249-3520
Elisa LaschiDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.
Marco CalderisiKode Solution srl, 56125 Pisa, Italy.
Maurizio GiordanoDepartment of Clinical Medicine and Surgery, Federico II University, 80131 Naples, Italy.ORCID 0000-0001-8568-4242
Giuseppe De BernardoDepartment of Woman and Child, Ospedale Buon Consiglio Fatebenefratelli, 80123 Naples, Italy.
Gianni ParigiDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.
Anna Laura ToniDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-1899-3007
Susanna EspositoDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Giuseppe BuonocoreDepartment of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-7921-7485

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prematurity is a risk factor for the development of chronic adult diseases. Metabolomics can correlate the biochemical changes to a determined phenotype, obtaining real information about the state of health of a subject at that precise moment. Significative differences in the metabolomic profile of preterm newborns compared to those born at term have been already identified at birth. An observational case-control study was performed at the University Hospital of Siena. The aim was to evaluate and compare the metabolomic profiles of young adults born preterm to those born at term. Urinary samples were collected from 67 young adults (18-23 years old) born preterm (mean gestational age of 30 weeks,

Indexed as

NMR spectroscopypreterm newbornurine samples

Identifiers

PMID34677412
PMCPMC8538752

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.