Evidence map›Paper›PMID 34677358›Full record

ArticleBiosensors2021

Enhanced Plasmonic Biosensor Utilizing Paired Antibody and Label-Free Fe

Samuel Husin Surya Mandala, Tai-Jan Liu, Chiung-Mei Chen, Kuo-Kang Liu, Mochamad Januar, Ying-Feng Chang, Chao-Sung Lai, Kuo-Hsuan Chang, Kou-Chen Liu

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Samuel Husin Surya MandalaDepartment of Electronic Engineering, Chang Gung University, Taoyuan 33302, Taiwan.
Tai-Jan LiuDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung 204, Taiwan.ORCID 0000-0002-5546-3323
Chiung-Mei ChenDepartment of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 33302, Taiwan.ORCID 0000-0002-0769-0353
Kuo-Kang LiuSchool of Engineering, University of Warwick, Coventry CV4 7AL, UK.ORCID 0000-0003-1871-9876
Mochamad JanuarDepartment of Electronic Engineering, Chang Gung University, Taoyuan 33302, Taiwan.
Ying-Feng ChangArtificial Intelligence Research Center, Chang Gung University, Taoyuan 33302, Taiwan.
Chao-Sung LaiDepartment of Electronic Engineering, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-2069-7533
Kuo-Hsuan ChangDepartment of Neurology, Chang Gung Memorial Hospital Linkou Medical Center and College of Medicine, Chang Gung University, Linkou 33305, Taiwan.ORCID 0000-0003-4972-9823
Kou-Chen LiuDepartment of Electronic Engineering, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-3294-3148
Chang Gung University · TWMing Chi University of Technology · TWChang Gung Memorial Hospital · TW

Funding

Chang Gung Memorial Hospital CMRPD2G0152Ministry of Science and Technology 107-2218-E- 467 182-008Ministry of Science and Technology 108-2218-E-182-004Ministry of Science and Technology 109-2221-E-182-021-MY3Ministry of Science and Technology 109-2221-E-182-063-MY3
6 · The paper itself

Abstract

Parkinson's disease (PD) is an acute and progressive neurodegenerative disorder, and diagnosis of the disease at its earliest stage is of paramount importance to improve the life expectancy of patients. α-Synuclein (α-syn) is a potential biomarker for the early diagnosis of PD, and there is a great need to develop a biosensing platform that precisely detects α-syn in human body fluids. Herein, we developed a surface plasmon resonance (SPR) biosensor based on the label-free iron oxide nanoparticles (Fe

Indexed as

Biosensing TechniquesNanoparticlesParkinson Diseasealpha-SynucleinAnimalsAntibodiesHumansMiceRabbitsSurface Plasmon Resonancealpha-SynucleinAntibodiesFe3O4 nanoparticleshuman serumpaired antibodyParkinson’s diseasesurface plasmon resonanceα-synuclein

Identifiers

PMID34677358
PMCPMC8534275
OpenAlexW3205666095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.