Evidence map›Paper›PMID 34677330›Full record

ArticleBiosensors2021

A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection.

Po-Chang Wu, Chao-Ping Pai, Mon-Juan Lee, Wei Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Po-Chang WuInstitute of Imaging and Biomedical Photonics, College of Photonics, National Yang Ming Chiao Tung University, Guiren Dist., Tainan 711010, Taiwan.
Chao-Ping PaiInstitute of Imaging and Biomedical Photonics, College of Photonics, National Yang Ming Chiao Tung University, Guiren Dist., Tainan 711010, Taiwan.
Mon-Juan LeeDepartment of Bioscience Technology, Chang Jung Christian University, Guiren Dist., Tainan 711301, Taiwan.ORCID 0000-0003-0420-6244
Wei LeeInstitute of Imaging and Biomedical Photonics, College of Photonics, National Yang Ming Chiao Tung University, Guiren Dist., Tainan 711010, Taiwan.ORCID 0000-0002-3515-1170
National Yang Ming Chiao Tung University · TWChang Jung Christian University · TW

Funding

Ministry of Science and Technology, Taiwan 107-2112-M-009-012-MY3Ministry of Science and Technology, Taiwan 109-2320-B-309-001Ministry of Science and Technology, Taiwan 110-2112-M-A49-023Ministry of Science and Technology, Taiwan 110-2320-B-309-001
6 · The paper itself

Abstract

A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10

Indexed as

Biosensing TechniquesLiquid CrystalsBiomarkers, TumorImmunoassaySerum Albumin, BovineBiomarkers, TumorSerum Albumin, Bovinebovine serum albumincancer biomarker CA125label-free biosensorliquid crystalsingle-substratespin-coating

Identifiers

PMID34677330
PMCPMC8533856
OpenAlexW3206731638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.