Evidence map›Paper›PMID 34677325›Full record

ArticleBiosensors2021

A Portable RT-LAMP/CRISPR Machine for Rapid COVID-19 Screening.

Meysam Rezaei, Sajad Razavi Bazaz, Dorsa Morshedi Rad, Olga Shimoni, Dayong Jin, William Rawlinson, Majid Ebrahimi Warkiani

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Protein Stacking on the APTES-Functionalized Pyrochlore BiACS applied materials & interfaces · 2025
    Article
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  10. CRISPR-Cas-Integrated LAMP.Biosensors · 2022
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Meysam RezaeiSchool of Biomedical Engineering, University of Technology Sydney, Sydney, NSW 2007, Australia.
Sajad Razavi BazazSchool of Biomedical Engineering, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0002-6419-3361
Dorsa Morshedi RadSchool of Biomedical Engineering, University of Technology Sydney, Sydney, NSW 2007, Australia.
Olga ShimoniInstitute for Biomedical Materials & Devices (IBMD), Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Dayong JinInstitute for Biomedical Materials & Devices (IBMD), Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0003-1046-2666
William RawlinsonSerology and Virology Division, NSW Health Pathology, Prince of Wales Hospital, Sydney, NSW 2031, Australia.ORCID 0000-0003-0988-7827
Majid Ebrahimi WarkianiSchool of Biomedical Engineering, University of Technology Sydney, Sydney, NSW 2007, Australia.
University of Technology Sydney · AUNew South Wales Department of Health · AU

Funding

Australian Research Council DP170103704Australian Research Council DP180103003National Health and Medical Research Council APP1143377
6 · The paper itself

Abstract

The COVID-19 pandemic has changed people's lives and has brought society to a sudden standstill, with lockdowns and social distancing as the preferred preventative measures. To lift these measurements and reduce society's burden, developing an easy-to-use, rapid, and portable system to detect SARS-CoV-2 is mandatory. To this end, we developed a portable and semi-automated device for SARS-CoV-2 detection based on reverse transcription loop-mediated isothermal amplification followed by a CRISPR/Cas12a reaction. The device contains a heater element mounted on a printed circuit board, a cooler fan, a proportional integral derivative controller to control the temperature, and designated areas for 0.2 mL Eppendorf

Indexed as

COVID-19COVID-19 TestingCRISPR-Cas SystemsHumansLimit of DetectionMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesPoint-of-Care SystemsRNA, ViralSARS-CoV-2RNA, ViralCOVID-19point of care testingrapid diagnosticsSARS-CoV-2

Identifiers

PMID34677325
PMCPMC8534004
OpenAlexW3203575763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.