ReviewCurrent oncology (Toronto, Ont.)2021
The Surgical Management of Proximal Femoral Metastases: A Narrative Review.
Review in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06863129 (Proximal FEmur Reconstruction or Internal Fixation fOR Metastases), which is not on this map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Randomized Controlled Trial
Who cites it
27 citing papers in PubMed.
- Perioperative Administration of Tranexamic Acid and Low Molecular Weight Heparin for Enhanced Blood Management in Intertrochanteric Fractures: A Randomized Controlled Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Trial
- Clinical outcomes of cement gun-assisted intramedullary nailing for femoral bone metastases: a retrospective case series.BMC musculoskeletal disorders · 2026Article
- Femur Fracture Risk Assessment in Patients with Lytic Metastases Using CT-Based Finite Element Models and Bone Crack Simulations Technique.Annals of biomedical engineering · 2026Article
- The necessity of cement augmentation in metastatic femur stabilization explored by finite element analysis.Scientific reports · 2026Article
- [Proximal femoral resection with endoprosthetic reconstruction for malignant bone tumors : Surgical technique via the anterior hip approach].Orthopadie (Heidelberg, Germany) · 2026Review
- Concurrent pathologic femoral shaft fracture in bone metastasis and acute myocardial infarction: a case report.Journal of surgical case reports · 2026Article
- Review
- Comparative outcomes of internal fixation versus prosthetic reconstruction in the treatment of proximal femoral metastases: a systematic review and meta-analysis.EFORT open reviews · 2025Article
- The influence of stem length on perioperative complications following cemented hip arthroplasty in metastatic femoral disease: A systematic review.Journal of orthopaedics · 2025Review
- Comparative Outcomes in Metastatic Spinal Cord Compression and Femoral Metastatic Disease: Distinct Clinical Entities with Divergent Prognoses?Medicina (Kaunas, Lithuania) · 2025Article
- What Is the Cumulative Incidence of Femoral Stem Revision and Stem Complication in Cemented and Uncemented Hip Arthroplasty for Proximal Femoral Metastatic Bone Disease?Clinical orthopaedics and related research · 2025Article
- Surgical management of metastatic lesions in the proximal femur: a systematic review.EFORT open reviews · 2025Article
- A comprehensive evaluation of intramedullary devices in the management of femoral metastasis: 30-day outcomes.Proceedings (Baylor University. Medical Center) · 2025Article
- High Fracture Risk of Femoral Bone Metastasis Treated with Palliative Radiotherapy in Recent Years.Current oncology (Toronto, Ont.) · 2024Article
- Palliative care of proximal femur metastatic disease and osteolytic lesions: results following surgical and radiation treatment.BMC cancer · 2024Article
- Article
- A Survey to Determine the Zone of Equipoise for the Proximal FEmur Resection or Internal Fixation fOR Metastases (PERFORM) Randomized Controlled Trial.Research square · 2024Article
- Proximal femoral multiple myeloma pathological fractures, impending and actual fractures - a patient survival study.BMC cancer · 2024Article
- Preoperative Albumin and Postoperative CRP/Albumin Ratio (CARS) are Independent Predictive Factors in Estimating 1-Year Mortality in Patients Operated for Proximal Femoral Metastasis with Endoprosthesis.Indian journal of orthopaedics · 2024Article
- Risk Factors for Early Postoperative Morbidity and Mortality following Extremity Metastatic Pathologic or Impending Fracture Fixation.International journal of surgical oncology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigations are required to ensure accurate diagnosis and prognosis. The goals of surgical management is to provide pain relief and return to function with a construct that provides stability to allow for immediate weightbearing. Current surgical treatment options include intramedullary nailing, hemiarthroplasty or total hip arthroplasty and endoprosthetic reconstructions. Oligometastatic renal cell carcinoma must be given special consideration as tumor resection and reconstruction has survival benefit. Both tumor and patient characteristics must be taken into account before deciding on the appropriate surgical intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.