Evidence map›Paper›PMID 34677187›Full record

ArticleJournal of cardiovascular development and disease2021

Left Cardiac Remodelling Assessed by Echocardiography Is Associated with Rho-Kinase Activation in Long-Distance Runners.

Felipe Contreras-Briceño, Julián Vega, Jorge Mandiola, María Paz Ocaranza, Sebastián Herrera, Manuel Salinas, Rodrigo Fernández, Jorge E Jalil, Sergio Lavandero, Mario Chiong and 4 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Felipe Contreras-BriceñoAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.ORCID 0000-0002-0674-7506
Julián VegaAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.ORCID 0000-0002-4425-661X
Jorge MandiolaAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.ORCID 0000-0003-3964-376X
María Paz OcaranzaAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.
Sebastián HerreraAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.
Manuel SalinasAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.
Rodrigo FernándezAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.
Jorge E JalilAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.
Sergio LavanderoAdvanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical & Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.ORCID 0000-0003-4258-1483
Mario ChiongAdvanced Center for Chronic Diseases (ACCDiS), Faculty of Chemical & Pharmaceutical Sciences & Faculty of Medicine, Universidad de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.ORCID 0000-0002-5174-6545
Paz GodoyAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.
Pablo F CastroAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.
Marta SitgesThorax Institute, IDIBAPS, Hospital Clinic, Av. Carrer del Rosselló #149, 08036 Barcelona, Spain.
Luigi GabrielliAdvanced Center for Chronic Diseases (ACCDiS), Division of Cardiovascular Diseases, Faculty of Medicine, Pontificia Universidad Católica de Chile, Av. Sergio Livingstone #1007, Santiago 8380492, Chile.

Funding

Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias 15130011Fondo Nacional de Ciencia y Tecnología 1170963
6 · The paper itself

Abstract

This single-blind and cross-sectional study evaluated the role of Rho-kinase (ROCK) as a biomarker of the cardiovascular remodelling process assessed by echocardiography in competitive long-distance runners (LDRs) during the training period before a marathon race. Thirty-six healthy male LDRs (37.0 ± 5.3 years; 174.0 ± 7.0 height; BMI: 23.8 ± 2.8; V˙ O

Indexed as

athlete’s heartcardiac biomarkersechocardiographyexercisefunctional cardiac capacity

Identifiers

PMID34677187
PMCPMC8541355

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.