Evidence map›Paper›PMID 34676909›Full record

ArticleJournal of neuroscience research2021

Mapping the corticoreticular pathway from cortex-wide anterograde axonal tracing in the mouse.

Pierce Boyne, Oluwole O Awosika, Yu Luo

Open access · greenAbstract read
In one paragraph

Article in Journal of neuroscience research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Pierce BoyneDepartment of Rehabilitation, Exercise and Nutrition Sciences, College of Allied Health Sciences, University of Cincinnati, Cincinnati, Ohio, USA.
Oluwole O AwosikaDepartment of Neurology and Rehabilitation Medicine, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Yu LuoDepartment of Molecular Genetics, Biochemistry and Microbiology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
University of Cincinnati Medical Center · USUniversity of Cincinnati · US

Funding

High-Intensity Interval Training to Recover Walking Post-Stroke: HIT-Stroke Trial 2R01HD093694 · NICHD · UNIVERSITY OF CINCINNATI · PI Pierce Boyne · 2018 to 2026
$6.1M
Modulating a critical inhibitory proteoglycan receptor to promote functional recovery after strokeR01NS107365 · NINDS · UNIVERSITY OF CINCINNATI · PI LUO, YU, SILVER, JERRY · 2019 to 2022
$1.4M
NICHD NIH HHS R01 HD093694NINDS NIH HHS L30 NS103347NINDS NIH HHS R01 NS107365
6 · The paper itself

Abstract

The corticoreticular pathway (CRP) has been implicated as an important mediator of motor recovery and rehabilitation after central nervous system damage. However, its origins, trajectory and laterality are not well understood. This study mapped the mouse CRP in comparison with the corticospinal tract (CST). We systematically searched the Allen Mouse Brain Connectivity Atlas (© 2011 Allen Institute for Brain Science) for experiments that used anterograde tracer injections into the right isocortex in mice. For each eligible experiment (N = 607), CRP and CST projection strength were quantified by the tracer volume reaching the reticular formation motor nuclei (RF

Indexed as

Motor CortexPyramidal TractsAnimalsAxonsBrain MappingBrain StemInternal CapsuleMicebrain mappingextrapyramidal tractslocomotionmotor activitypostural balancepyramidal tracts

Identifiers

PMID34676909
PMCPMC8714061
OpenAlexW3206612219

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.