Evidence map›Paper›PMID 34676870›Full record

ArticleSleep2022

Longitudinal association of actigraphy-assessed sleep with physical growth in the first 6 months of life.

Xiaoyu Li, Sebastien Haneuse, Michael Rueschman, Emily R Kaplan, Xinting Yu, Kirsten K Davison, Susan Redline, Elsie M Taveras

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sleep, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06117631 (First Thousand Days), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06117631 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

First Thousand Days: Prevention of Early Life Obesity in Latino Infants and Toddlers

TypeinterventionalSponsorUniversity of Texas at AustinRan2023 to 2027Enrolled256ConditionsInfant Overweight, Infant Obesity, Infant Overnutrition, Infant DevelopmentArmsCentering Parenting, Bright by Text
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
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  4. Early-life NOThe Lancet regional health. Western Pacific · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xiaoyu LiDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-4463-9944
Sebastien HaneuseDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Michael RueschmanDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-0506-8368
Emily R KaplanDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Xinting YuDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-7497-0101
Kirsten K DavisonSchool of Social Work, Boston College, Boston, MA, USA.
Susan RedlineDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Elsie M TaverasDivision of General Academic Pediatrics, Massachusetts General Hospital for Children, Boston, MA, USA.
Brigham and Women's Hospital · USBoston College · USHarvard University · US

Funding

New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Phenotypic and Molecular Signatures for Sleep Apnea and Related MorbiditiesR35HL135818 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S. · 2017 to 2023
$7.2M
Infant Sleep Patterns and Accelerated Growth Trajectories from Birth to 24 monthsR01DK107972 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI DAVISON, KIRSTEN, REDLINE, SUSAN S. · 2015 to 2019
$4.0M
Patient Oriented Research and Mentorship in Childhood Obesity DisparitiesK24DK105989 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI TAVERAS BENAVIDEZ, ELSIE MIREYA · 2015 to 2019
$907k
Patient Oriented Research and Mentorship in Childhood Obesity DisparitiesK24HL159680 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI TAVERAS BENAVIDEZ, ELSIE MIREYA · 2021 to 2025
$510k
HRSA HHS R40MC32753NHLBI NIH HHS K24 HL159680NHLBI NIH HHS R35 HL135818NIDDK NIH HHS K24 DK105989NIDDK NIH HHS P30 DK111022NIDDK NIH HHS R01 DK107972
6 · The paper itself

Abstract

STUDY

objectivesSuboptimal sleep is associated with obesity and its sequelae in children and adults. However, few studies have examined the association between sleep and physical growth in infants who experience rapid changes in sleep/wake patterns. We examined the longitudinal association of changes in objectively assessed sleep/wake patterns with changes in growth between ages 1 and 6 months.

methodsWe studied 298 full-term infants in the longitudinal Rise & SHINE cohort study. Changes from 1 and 6 months in nighttime sleep duration, wake after sleep onset (WASO), and number of waking bouts ≥5 min were assessed using ankle actigraphy. Overweight was defined as age- and sex-specific weight for length ≥95th percentile. Generalized estimating equation analyses adjusted for infants' and mothers' characteristics.

resultsThe mean (SD) birth weight was 3.4 (0.4) kg; 48.7% were boys. In multivariable adjusted models, each 1-h increase in nighttime sleep duration between months 1 and 6 was associated with a 26% decrease in the odds of overweight from 1 to 6 months (odds ratio [OR] = 0.74; 95% confidence interval [CI, 0.56, 0.98]). Each 1-unit decrease in number of waking bouts was associated with a 16% decrease in the odds of overweight (OR = 0.84; 95% CI [0.72, 0.98]). Changes in WASO were not associated with the odds of overweight.

conclusionsGreater increases in nighttime sleep duration and more consolidation of nighttime sleep were associated with lower odds of overweight from 1 to 6 months. Adverse sleep patterns as early as infancy may contribute to excess adiposity.

Indexed as

ActigraphySleepAdultChildCohort StudiesFemaleHumansInfantMaleMothersPolysomnographyactigraphyinfantphysical growthsleep

Identifiers

PMID34676870
PMCPMC8754492
OpenAlexW3207246654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.