Evidence map›Paper›PMID 34676627›Full record

ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2022

Predictive impacts of chronic kidney disease and cardiac sympathetic nervous activity on lethal arrhythmic events in chronic heart failure.

Kazuaki Amami, Shinya Yamada, Akiomi Yoshihisa, Takashi Kaneshiro, Naoko Hijioka, Minoru Nodera, Takeshi Nehashi, Yasuchika Takeishi

Open access · goldAbstract read
In one paragraph

Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. European journal of nuclear medicine and molecular imaging · 2023
    Review
  5. Predictive impacts of chronic kidney disease and cardiac sympathetic nervous activity on lethal arrhythmic events in chronic heart failure.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kazuaki AmamiDepartment of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
Shinya YamadaDepartment of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.ORCID 0000-0001-5726-3926
Akiomi YoshihisaDepartment of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
Takashi KaneshiroDepartment of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
Naoko HijiokaDepartment of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
Minoru NoderaDepartment of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
Takeshi NehashiDepartment of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
Yasuchika TakeishiDepartment of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
Fukushima Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe clinical implications of chronic kidney disease (CKD) and cardiac sympathetic nervous activity (CSNA) regarding lethal arrhythmic events have not yet been fully elucidated in patients with chronic heart failure (CHF). We hypothesized that the combination of CKD and abnormal CSNA, assessed by

methodsWe studied 165 consecutive hospitalized CHF patients without dialysis. Cardiac

resultsDuring a median follow-up of 5.3 years, lethal arrhythmic events were observed in 40 patients (24.2%). The patients were divided into four groups according to the presence of CKD and CSNA abnormality: non-CKD/normal CSNA (n = 52), CKD/normal CSNA (n = 39), non-CKD/abnormal CSNA (n = 33), and CKD/abnormal CSNA (n = 41). Kaplan-Meier analysis showed that CKD/abnormal CSNA had the highest event rate (log-rank p = .004). Additionally, the Cox proportional hazard analysis revealed that CKD/abnormal CSNA was a predictor for lethal arrhythmic events compared with non-CKD/normal CSNA (hazard ratio, 5.368, p = .001). However, the other two groups did not show significant differences compared with the non-CKD/normal CSNA group.

conclusionsThe combination of CKD and abnormal CSNA, assessed by

Indexed as

Defibrillators, ImplantableHeart FailureRenal Insufficiency, Chronic3-IodobenzylguanidineChronic DiseaseElectrocardiographyHeartHumansPrognosis3-Iodobenzylguanidine123I-metaiodobenzylguanidine scintigraphycardiac sympathetic nervous activitychronic kidney diseasesudden cardiac deathventricular tachyarrhythmia

Identifiers

PMID34676627
PMCPMC8739613
OpenAlexW3207735737

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.