ArticleEuropean geriatric medicine2022
Medication-related quality of life (MRQoL) in ambulatory older adults with multi-morbidity and polypharmacy.
Article in European geriatric medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interventions to improve the appropriate use of polypharmacy for older people.The Cochrane database of systematic reviews · 2023Pooled it
- Medication-related Burden and Experience With Medications in Indonesian Older Adults With Chronic Diseases: A Mixed-method Study.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025Article
- The association between medication use and health-related quality of life in multimorbid older patients with polypharmacy.European geriatric medicine · 2024Article
- Selection of outcome measurement instruments for a core outcome set for trials aimed at improving appropriate polypharmacy in older people in primary care: a Delphi consensus study.International journal of clinical pharmacy · 2024Article
- Measuring Quality of Life in Deprescribing Trials: A Scoping Review.Drugs & aging · 2024Article
- Prevalence of polypharmacy and medication-related quality of life among adult patients in Al-Ahsa, Saudi Arabia.Journal of medicine and life · 2023Article
- Correlation between the number of patient-reported adverse events, adverse drug events, and quality of life in older patients: an observational study.International journal of clinical pharmacy · 2022Observational
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess medication-related quality-of-life (MRQoL) in multi-morbid older adults with polypharmacy and correlations with medications, frailty and health-related QoL.
methodsWith a cross sectional study of multi-morbid geriatric medicine outpatients, we assessed MRQoL (MRQol-LSv1), frailty status, potentially inappropriate medications, Medication Adherence Rating Scale (MARS), health-related-QoL (Short-Form 12, SF12) and medication burden (Living with Medicines Questionnaire, LMQv2).
resultsOne-in-four (n = 59) of 234 outpatient attendees met inclusion criteria. Almost half (n = 106, 45%) were excluded due to cognition (MMSE < 26). Included participants (n = 27, mean age 80.2 years) experienced a median of 11 (IQR 9-13.5) co-morbidities and were prescribed a median of 10 (IQR 8-12.25) medications. Overall, MRQoL-LS.v.1 scores were low, suggesting good medication-related quality of life (median MRQoL-LS.v.1 score of 14, IQR 14-22). Correlations between MRQoL, number of daily medications, co-morbidity burden, LMQv2 score, SF12 scores and number of PIMs were non-significant.
conclusionMRQoL-LSv.1 is unsuitable for most patients attending geriatric ambulatory services.
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