Evidence map›Paper›PMID 34676212›Full record

ArticleFrontiers in cell and developmental biology2021

SNHG10 Is a Prognostic Biomarker Correlated With Immune Infiltrates in Prostate Cancer.

Qiang Chen, Xiaorong Yang, Binbin Gong, Wenjie Xie, Ming Ma, Shengqiang Fu, Siyuan Wang, Yutang Liu, Zhicheng Zhang, Ting Sun and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Qiang ChenDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Xiaorong YangDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Binbin GongDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Wenjie XieDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Ming MaDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Shengqiang FuDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Siyuan WangDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yutang LiuDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zhicheng ZhangDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Ting SunDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zhilong LiDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Nanchang University · CNFirst Affiliated Hospital of Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SNHG10 is a long non-coding RNA (lncRNA) found to be overexpressed in multiple human cancers including prostate cancer (PC). However, the underlying mechanisms of SNHG10 driving the progression of PC remains unclear. In this study, we investigated the role of SNHG10 in PC and found that SNHG10 expression was significantly increased in datasets extracted from The Cancer Genome Atlas. Increased expression of SNHG10 was related to advanced clinical parameters. Receiver operating curve analysis revealed the significant diagnostic ability of SNHG10 (AUC = 0.805). In addition, immune infiltration analysis, and GSEA showed that SNHG10 expression was correlated with oxidative phosphorylation and immune infiltrated cells. Finally, we determined that SNHG10 regulated cell proliferation, migration, and invasion of PC

Indexed as

biomarkerprognosisproliferationprostate cancerSNHG10

Identifiers

PMID34676212
PMCPMC8523833
OpenAlexW3204899180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.