Evidence map›Paper›PMID 34676183›Full record

ArticleFrontiers in pediatrics2021

Analysis of Global and Local DNA Methylation Patterns in Blood Samples of Patients With Autism Spectrum Disorder.

María Victoria García-Ortiz, María José de la Torre-Aguilar, Teresa Morales-Ruiz, Antonio Gómez-Fernández, Katherine Flores-Rojas, Mercedes Gil-Campos, Pilar Martin-Borreguero, Rafael R Ariza, Teresa Roldán-Arjona, Juan Luis Perez-Navero

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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  11. Nerve Growth Factor and Autoimmune Diseases.Current issues in molecular biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

María Victoria García-OrtizMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
María José de la Torre-AguilarMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Teresa Morales-RuizMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Antonio Gómez-FernándezMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Katherine Flores-RojasMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Mercedes Gil-CamposMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Pilar Martin-BorregueroMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Rafael R ArizaMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Teresa Roldán-ArjonaMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Juan Luis Perez-NaveroMaimónides Biomedical Research Institute of Córdoba (IMIBIC), Córdoba, Spain.
Instituto Maimónides de Investigación Biomédica de Córdoba · ESHospital Universitario Reina Sofía · ESInstituto de Salud Carlos III · ESUniversity of Córdoba · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this investigation was to determine whether there are alterations in DNA methylation patterns in children with autism spectrum disorder (ASD).

Indexed as

autism spectrum disorderDNA methylation patternsNCAMneurodevelopmental regressionNGF

Identifiers

PMID34676183
PMCPMC8524094
OpenAlexW3204201847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.