ArticleNational science review2021
Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation.
Article in National science review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Developmental chronology of mouse embryo from 2-cell stage through birth.Nature cell biology · 2026Article
- LL-37 Inhibits TMPRSS2-Mediated S2' Site Cleavage and SARS-CoV-2 Infection but Not Omicron Variants.Cell proliferation · 2025Article
- Enhancing human ACE2 expression in mouse models to improve COVID-19 research.FEBS open bio · 2025Article
- Premature aging effects on COVID-19 pathogenesis: new insights from mouse models.Scientific reports · 2024Article
- Mast cell degranulation-triggered by SARS-CoV-2 induces tracheal-bronchial epithelial inflammation and injury.Virologica Sinica · 2024Article
- Emerging Landscape of Preclinical Models for Studying COVID-19 Neurologic Diseases.ACS pharmacology & translational science · 2023Review
- An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Editorial: Deleterious and beneficial humoral immune response in viral diseases: Two sides of the same coin.Frontiers in immunology · 2023Article
- A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection.Journal of virology · 2022Article
- SARS-CoV-2-triggered mast cell rapid degranulation induces alveolar epithelial inflammation and lung injury.Signal transduction and targeted therapy · 2021Article
- Animal models for SARS-CoV-2 infection and pathology.MedComm · 2021Review
- Captopril alleviates lung inflammation in SARS-CoV-2-infected hypertensive mice.Zoological research · 2021Article
- Establishment of a humanized swine model for COVID-19.Cell discovery · 2021Article
- SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target.Cell research · 2021Article
- Models and Mechanisms for COVID-19 Research.Disease models & mechanisms · 2021Article
- Particulate matter exposure exacerbates susceptibility to SARS-CoV-2 infection in humanized ACE2 mice.Zoological research · 2021Article
- Application of the humanized mouse model in research into SARS-CoV-2 infection (Review).Medicine internationalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.