Evidence map›Paper›PMID 34676053›Full record

ArticleOncotarget2021

Association of four genetic variants with colorectal cancer in Kazakhstan population.

Yevgeniya Kolesnikova, Dmitriy Babenko, Irina Kadyrova, Svetlana Kolesnichenko, Lyudmila Akhmaltdinova, Ilya Korshukov, Naylya Kabildina, Valentina Sirota, Vera Zhumaliyeva, Dana Taizhanova and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yevgeniya KolesnikovaDepartment of Biomedicine, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Dmitriy BabenkoResearch and Scientific Center, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Irina KadyrovaShared Resource Laboratory, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Svetlana KolesnichenkoShared Resource Laboratory, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Lyudmila AkhmaltdinovaShared Resource Laboratory, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Ilya KorshukovShared Resource Laboratory, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Naylya KabildinaDepartment of Oncology and Radiation Diagnostics, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Valentina SirotaDepartment of Oncology and Radiation Diagnostics, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Vera ZhumaliyevaDepartment of Oncology and Radiation Diagnostics, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Dana TaizhanovaDepartment of Internal Medicine, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Dmitriy VazenmillerDepartment of Obstetrics, Gynecology and Perinatology, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Anar TurmukhambetovaDepartment of Strategic Development and Science, Karaganda Medical University, Karaganda 100008, Kazakhstan.
Karaganda Medical University · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study was conducted to search for polymorphisms located in the 10th chromosome associated with colorectal adenocarcinoma in representatives of the Kazakhstan population. Study was performed with 282 colorectal cancer (CRC) patients and 159 controls. Genotyping of SNPs was performed by QuantStudio 12K Flex PCR. For four significant SNPs inheritance model analysis was performed. Increasing risk of CRC was noted for rs10795668 in log-additive model (OR = 1.45, 95% CI: 1.05-1.99,

Indexed as

colorectal adenocarcinomars1035209rs10506868rs10795668rs11190164

Identifiers

PMID34676053
PMCPMC8522836
OpenAlexW3200219975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.