Evidence map›Paper›PMID 34675974›Full record

ReviewInterdisciplinary perspectives on infectious diseases2021

The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa.

Sylvain Raoul Simeni Njonnou, Nadia Christelle Noumedem Anangmo, Fernando Kemta Lekpa, Diomede Noukeu Njinkui, Dominique Enyama, Christian Ngongang Ouankou, Eric Vounsia Balti, Esther Astrid Mbono Samba Eloumba, Jean Roger Moulion Tapouh, Simeon Pierre Choukem

Abstract readReview
In one paragraph

Review in Interdisciplinary perspectives on infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sylvain Raoul Simeni NjonnouDepartment of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.ORCID https://orcid.org/0000-0002-5050-566X
Nadia Christelle Noumedem AnangmoDepartment of Microbiology, Haematology and Immunology, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.ORCID https://orcid.org/0000-0002-2393-9841
Fernando Kemta LekpaDepartment of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.ORCID https://orcid.org/0000-0001-7592-5049
Diomede Noukeu NjinkuiThe University of Dschang Taskforce for the Elimination of COVID-19 (UNITED#COVID-19), Dschang, Cameroon.ORCID https://orcid.org/0000-0003-3640-6873
Dominique EnyamaThe University of Dschang Taskforce for the Elimination of COVID-19 (UNITED#COVID-19), Dschang, Cameroon.ORCID https://orcid.org/0000-0001-5792-9476
Christian Ngongang OuankouDepartment of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.ORCID https://orcid.org/0000-0002-1630-4944
Eric Vounsia BaltiDepartment of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.ORCID https://orcid.org/0000-0003-4445-308X
Esther Astrid Mbono Samba EloumbaEndocrine and Diabetes Unit and National Obesity Centre, Department of Internal Medicine, Yaounde Central Hospital, Yaounde, Cameroon.ORCID https://orcid.org/0000-0003-3828-7580
Jean Roger Moulion TapouhThe University of Dschang Taskforce for the Elimination of COVID-19 (UNITED#COVID-19), Dschang, Cameroon.ORCID https://orcid.org/0000-0001-6570-3661
Simeon Pierre ChoukemDepartment of Internal Medicine and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.ORCID https://orcid.org/0000-0003-1399-5513

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite some cases of severe or critical manifestations of the coronavirus disease 2019 (COVID-19) described among children, the prevalence of this infection in the pediatric population is quite low worldwide, particularly in sub-Saharan Africa. Current data suggest indeed that, independent of the population considered overall, severe and critical cases of COVID-19 are rare among children. This observation prompted us to discuss the possible hypotheses which could explain the low prevalence of COVID-19 among children; amongst others, we discuss (1) immunomodulation by the Bacillus Calmette-Guerin vaccine or by some parasitic infections such as malaria, schistosomiasis, and helminthiasis and (2) cross immunization with other coronaviruses commonly found in the sub-Saharan African setting.

Identifiers

PMID34675974
PMCPMC8526265

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.