Evidence map›Paper›PMID 34675886›Full record

Trial reportFrontiers in endocrinology2021

Discordance Between Glucose Levels Measured in Interstitial Fluid

Kristine Færch, Hanan Amadid, Lea Bruhn, Kim Katrine Bjerring Clemmensen, Adam Hulman, Mathias Ried-Larsen, Martin Bæk Blond, Marit Eika Jørgensen, Dorte Vistisen

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kristine FærchSteno Diabetes Center Copenhagen, Gentofte, Denmark.
Hanan AmadidSteno Diabetes Center Copenhagen, Gentofte, Denmark.
Lea BruhnSteno Diabetes Center Copenhagen, Gentofte, Denmark.
Kim Katrine Bjerring ClemmensenSteno Diabetes Center Copenhagen, Gentofte, Denmark.
Adam HulmanSteno Diabetes Center Aarhus, Aarhus, Denmark.
Mathias Ried-LarsenCentre for Physical Activity Research, Rigshospitalet, Copenhagen, Denmark.
Martin Bæk BlondSteno Diabetes Center Copenhagen, Gentofte, Denmark.
Marit Eika JørgensenSteno Diabetes Center Copenhagen, Gentofte, Denmark.
Dorte VistisenSteno Diabetes Center Copenhagen, Gentofte, Denmark.
Steno Diabetes Centers · DKUniversity of Copenhagen · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The oral glucose tolerance test (OGTT) is together with haemoglobin A Methods: 120 adults with prediabetes defined by HbA Results: A total of 306 OGTTs with simultaneous CGM measurements were obtained. Except in fasting, the CGM glucose values were below the OGTT values throughout the OGTT period with mean (SD) differences of 0.2 (0.7) mmol/L at time 0 min, -1.1 (1.3) at 30 min, -1.4 (1.8) at 60 min, and -0.5 (1.1) at 120 min). For measurements at 0 and 120 min, there was a proportional bias with an increasing mean difference between CGM and OGTT values with increasing mean of the two measurements. Conclusions: Due to poor agreement between the OGTT and CGM with wide 95% limits of agreement and proportional bias at 0 and 120 min, the potential for assessing glucose tolerance in prediabetes using CGM is questionable.

Indexed as

Administration, OralAgedBlood GlucoseExtracellular FluidFemaleGlucoseGlucose Tolerance TestGlycated HemoglobinHumansMaleMiddle AgedObesityOverweightPrediabetic StateBlood GlucoseGlucoseGlycated HemoglobinBland-Altmancontinuous glucose monitor systemoral glucose challenge testprediabetesproportional bias

Identifiers

PMID34675886
PMCPMC8525890
OpenAlexW3202539771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.