Evidence map›Paper›PMID 34675807›Full record

ReviewFrontiers in pharmacology2021

A Review on Drug Delivery System for Tumor Therapy.

Guoxiang Liu, Lina Yang, Guang Chen, Fenghua Xu, Fanghao Yang, Huaxin Yu, Lingne Li, Xiaolei Dong, Jingjing Han, Can Cao and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 125 citations in OpenAlex.

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  13. ATP-Powered Signaling Between Artificial and Living Cells.Angewandte Chemie (International ed. in English) · 2025
    Article
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Guoxiang LiuDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Lina YangDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Guang ChenDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Fenghua XuDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Fanghao YangDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Huaxin YuDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Lingne LiDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Xiaolei DongDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Jingjing HanDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Can CaoDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Jingyu QiDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Junzhe SuDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Xiaohui XuDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Xiaoxia LiDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Bing LiDepartment of Genetics and Cell Biology, Basic Medical College, Qingdao University, Qingdao, China.
Qingdao University · CNAffiliated Hospital of Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, with the development of nanomaterials, the research of drug delivery systems has become a new field of cancer therapy. Compared with conventional antitumor drugs, drug delivery systems such as drug nanoparticles (NPs) are expected to have more advantages in antineoplastic effects, including easy preparation, high efficiency, low toxicity, especially active tumor-targeting ability. Drug delivery systems are usually composed of delivery carriers, antitumor drugs, and even target molecules. At present, there are few comprehensive reports on a summary of drug delivery systems applied for tumor therapy. This review introduces the preparation, characteristics, and applications of several common delivery carriers and expounds the antitumor mechanism of different antitumor drugs in delivery carriers in detail which provides a more theoretical basis for clinical application of personalized cancer nanomedicine in the future.

Indexed as

antitumor drugdelivery carriersdrug delivery systemtargetingtumor therapy

Identifiers

PMID34675807
PMCPMC8524443
OpenAlexW3202226773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.