Evidence map›Paper›PMID 34675794›Full record

ArticleFrontiers in synaptic neuroscience2021

Somatostatin Neurons in the Mouse Pontine Nucleus Activate GABA

Selena Garcia DuBar, Daniela Cosio, Holly Korthas, Jason P Van Batavia, Stephen A Zderic, Niaz Sahibzada, Rita J Valentino, Stefano Vicini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in synaptic neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Selena Garcia DuBarDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, United States.
Daniela CosioDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, United States.
Holly KorthasInterdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, United States.
Jason P Van BataviaDivision of Urology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Stephen A ZdericDivision of Urology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Niaz SahibzadaDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, United States.
Rita J ValentinoDepartment of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Stefano ViciniDepartment of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, United States.
Children's Hospital of Philadelphia · USGeorgetown University · USGeorgetown University Medical Center · US

Funding

Training in Neural Injury &PlasticityT32NS041218 · NINDS · GEORGETOWN UNIVERSITY · PI MARK P BURNS, Kathleen Anne Maguire-Zeiss · 2001 to 2026
$3.5M
Defining the role of CRH-expressing neurons in Barrington's Nucleus (BN) and Characterizing the other neuronal subpopulations in BNK08DK120934 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI VAN BATAVIA, JASON PHILIP · 2019 to 2022
$695k
NIDDK NIH HHS K08 DK120934NIDDK NIH HHS L40 DK122486NINDS NIH HHS T32 NS041218
6 · The paper itself

Abstract

The pontine nuclei comprising the locus coeruleus (LC) and Barrington's nucleus (BRN) amongst others form the neural circuitry(s) that coordinates arousal and voiding behaviors. However, little is known about the synaptic connectivity of neurons within or across these nuclei. These include corticotropin-releasing factor (CRF

Indexed as

arousalchannelrhodopsin (ChR2)corticotropin releasing factor (CRF)GABAA receptoroptogeneticpatch-clamppontine micturition centersomatostatin (SST)

Identifiers

PMID34675794
PMCPMC8524133
OpenAlexW3207114906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.