Evidence map›Paper›PMID 34675781›Full record

ReviewFrontiers in neural circuits2021

Genetic Transsynaptic Techniques for Mapping Neural Circuits in

Lina Ni

Abstract readReview
In one paragraph

Review in Frontiers in neural circuits, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Lina NiSchool of Neuroscience, Virginia Tech, Blacksburg, VA, United States.

Funding

Demonstrate the molecular receptor and functions of dorsal organ warm cells in fliesR01GM140130 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI NI, LINA · 2021 to 2025
$1.7M
Develop functional trans-Tango to identify higher-order neurons with determined functionsR21MH122987 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI NI, LINA · 2020 to 2020
$432k
NIGMS NIH HHS R01 GM140130NIMH NIH HHS R21 MH122987
6 · The paper itself

Abstract

A neural circuit is composed of a population of neurons that are interconnected by synapses and carry out a specific function when activated. It is the structural framework for all brain functions. Its impairments often cause diseases in the nervous system. To understand computations and functions in a brain circuit, it is of crucial importance to identify how neurons in this circuit are connected. Genetic transsynaptic techniques provide opportunities to efficiently answer this question. These techniques label synapses or across synapses to unbiasedly label synaptic partners. They allow for mapping neural circuits with high reproducibility and throughput, as well as provide genetic access to synaptically connected neurons that enables visualization and manipulation of these neurons simultaneously. This review focuses on three recently developed

Indexed as

DrosophilaSynapsesAnimalsNeural PathwaysNeuronsReproducibility of ResultsBAcTraceDrosophilaneural circuitsTRACTtranssynaptic labelingtrans-Tango

Identifiers

PMID34675781
PMCPMC8524129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.