Evidence map›Paper›PMID 34675722›Full record

ArticleNature and science of sleep2021

Risk Factors for Sleepiness at the Wheel and Sleep-Related Car Accidents Among Patients with Obstructive Sleep Apnea: Data from the French Pays de la Loire Sleep Cohort.

AbdelKebir Sabil, Remi Bignard, Chloé Gervès-Pinquié, Pierre Philip, Marc Le Vaillant, Wojciech Trzepizur, Nicole Meslier, Frédéric Gagnadoux

Registry-linked trialAbstract read
In one paragraph

Article in Nature and science of sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06117579 (Effect of Inspiratory Muscle Training on Daytime Sleepiness in Obstructive Sleep Apnea Syndrome), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06117579 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Inspiratory Muscle Training on Daytime Sleepiness in Obstructive Sleep Apnea Syndrome : Prospective Randomized Controlled Trial

TypeinterventionalSponsorCentre Hospitalier Régional d'OrléansRan2024 to 2027Enrolled58ConditionsObstructive Sleep Apnea of AdultArmsInspiratory muscle training
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Bordeaux Sleepiness Scale (BOSS): a new questionnaire to measure sleep-related driving risk.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

AbdelKebir SabilClinical Research Department, Cloud Sleep Lab, Paris, France.
Remi BignardDepartment of Respiratory and Sleep Medicine, University Hospital of Angers, Angers, France.
Chloé Gervès-PinquiéBiostatistics Department, Pays de la Loire Respiratory Health Research Institute, Beaucouzé, France.
Pierre PhilipSleep, Attention and Neuropsychiatry Unit, University of Bordeaux, CNRS, SANPSY USR 3413, and CHU Pellegrin, Bordeaux, France.
Marc Le VaillantBiostatistics Department, Pays de la Loire Respiratory Health Research Institute, Beaucouzé, France.
Wojciech TrzepizurDepartment of Respiratory and Sleep Medicine, University Hospital of Angers, Angers, France.
Nicole MeslierDepartment of Respiratory and Sleep Medicine, University Hospital of Angers, Angers, France.ORCID 0000-0002-3497-5688
Frédéric GagnadouxDepartment of Respiratory and Sleep Medicine, University Hospital of Angers, Angers, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to determine the risk factors of sleepiness at the wheel among patients with obstructive sleep apnea (OSA) and to determine factors that were independently associated with reported sleep-related near-miss accidents or car accidents. PATIENTS AND

methodsThis retrospective study was conducted on 843 OSA patients from the French Pays de la Loire sleep cohort database. Each patient completed surveys including anthropometric data, medical history, professional status, and data on alcohol and tobacco use. Epworth sleepiness scale (ESS) and sleep quality questionnaires were administered. Regarding driving, data were collected on occurrence of sleepiness-related near-misses or car accidents, and on distance driven per year. The primary dependent variable of interest was reported sleepiness at the wheel.

resultsOn multivariable regression analysis, reported sleepiness at the wheel (n=298) was independently associated with younger age (p=0.02), male gender (p=0.009), marked nocturnal hypoxemia (p=0.006), lower BMI (p=0.03), absence of cardiovascular disease (p=0.022), executives or high degree jobs (p=0.003) and reported difficulty-maintaining sleep (p=0.03). Only past experience of sleepiness at the wheel (OR 12.18, [6.38-23.25]) and an ESS ≥11 (OR 4.75 [2.73-8.27]) were independently associated with reported car accidents (n=30) or near-miss accidents (n=137).

conclusionIn patients newly diagnosed with OSA, the risk of car accident seems multifactorial, and its evaluation should include multiple parameters such as patient self-reported sleepiness at the wheel, occurrence of sleepiness-related accidents, anthropometry, professional status, and insomnia complaints. Thus, it is possible to evaluate this risk and advise patients as early as the first visit at the sleep medicine clinic without waiting for the results of the sleep study.

Indexed as

accidentsearly risk predictionFrench driversnear-miss accidentsOSAsleepiness

Identifiers

PMID34675722
PMCPMC8502051

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.