Evidence map›Paper›PMID 34675681›Full record

ReviewClinical epidemiology2021

Existing Data Sources for Clinical Epidemiology: The Danish Study Group of Infections of the Brain Database (DASGIB).

Jacob Bodilsen, Lykke Larsen, Christian Thomas Brandt, Lothar Wiese, Birgitte Rønde Hansen, Christian Østergaard Andersen, Hans Rudolf Lüttichau, Jannik Helweg-Larsen, Merete Storgaard, Henrik Nielsen

Abstract readReview
In one paragraph

Review in Clinical epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Herpes Simplex Virus Type 1 Encephalitis: A Prospective Population-Based Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Group A Streptococcus Meningitis in Adults, Denmark.Emerging infectious diseases · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jacob BodilsenDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg, 9000, Denmark.ORCID 0000-0002-7398-814X
Lykke LarsenDepartment of Infectious Diseases, Odense University Hospital, Odense, 5000, Denmark.ORCID 0000-0002-4113-4182
Christian Thomas BrandtDepartment of Infectious Diseases, Nordsjællands Hospital, Hillerød, 3400, Denmark.
Lothar WieseDepartment of Infectious Diseases, Sjælland University Hospital, Roskilde, 4000, Denmark.
Birgitte Rønde HansenDepartment of Infectious Diseases, Hvidovre University Hospital, Copenhagen, 2650, Denmark.
Christian Østergaard AndersenDepartment of Clinical Microbiology, Hvidovre University Hospital, Copenhagen, 2650, Denmark.
Hans Rudolf LüttichauDepartment of Infectious Diseases, Herlev Gentofte Hospital, Copenhagen, 2730, Denmark.ORCID 0000-0002-5428-4075
Jannik Helweg-LarsenDepartment of Infectious Diseases, Rigshospitalet, Copenhagen, 2100, Denmark.
Merete StorgaardDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, 8200, Denmark.
Henrik NielsenDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg, 9000, Denmark.ORCID 0000-0002-0841-8255

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central nervous system (CNS) infections are rare diseases that are associated with considerable morbidity and mortality. Increased knowledge based on contemporary data is a prerequisite for improved management and prevention of these serious conditions. Yet, population-based databases of patients hospitalized with CNS infections remain scarce. The Danish Study Group of Infections of the Brain (DASGIB) has prospectively registered information on all adults ≥18 years of age admitted with CNS infections at departments of infectious diseases in Denmark since 2015. The main variables collected are baseline demographics, blood and cerebrospinal fluid tests, imaging results, and outcome using the Glasgow Outcome Scale score. To investigate important aspects for each type of CNS infections, additional variables are included specifically for bacterial meningitis, viral meningitis, encephalitis, brain abscess, neurosyphilis, and Lyme neuroborreliosis. From 2015 to 2020, a total of 3579 cases of CNS infections have been recorded in the DASGIB database. Using the unique civil registration number assigned to all Danish residents, the database can be unambiguously linked with nationwide healthcare registries at the individual level. This enables researchers to conduct detailed population-based and longitudinal observational studies of risk and prognosis of CNS infections and to compare them with matched population cohorts. The database is well-suited for epidemiological research and the DASGIB network forms a solid infrastructure for future national and international collaborations.

Indexed as

bacterial meningitisborreliosisbrain abscesscerebral abscessCNS infectionscohort studiesdatabaseencephalitisepidemiologyLyme neuroborreliosisneurosyphilissyphilisviral meningitis

Identifiers

PMID34675681
PMCPMC8500496

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.