Evidence map›Paper›PMID 34675610›Full record

ArticleInternational journal of general medicine2021

Withdrawal of Glucocorticoid Therapy is Difficult in Women with Polymyalgia Rheumatica: An Observational Study.

Dai Aoki, Nobuyuki Kajiwara, Keiko Irishio, Yasuhiro Kato, Shinya Suezaki, Misaki Kageyama, Masahiro Misago, Daisuke Tamai, Shinichiro Nakao, Takato Ueoka and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Dai AokiDepartment of Emergency and General Medicine, Ikeda City Hospital, Ikeda, Osaka, Japan.
Nobuyuki KajiwaraDepartment of Nephrology, Ikeda City Hospital, Ikeda, Osaka, Japan.ORCID 0000-0001-7017-4354
Keiko IrishioDepartment of Clinical Research, Ikeda City Hospital, Ikeda, Osaka, Japan.
Yasuhiro KatoDepartment of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.ORCID 0000-0002-4050-2350
Shinya SuezakiDepartment of Emergency and General Medicine, Ikeda City Hospital, Ikeda, Osaka, Japan.
Misaki KageyamaDepartment of Emergency and General Medicine, Ikeda City Hospital, Ikeda, Osaka, Japan.
Masahiro MisagoDepartment of Emergency and General Medicine, Ikeda City Hospital, Ikeda, Osaka, Japan.
Daisuke TamaiTamai Medical Clinic, Hannan, Osaka, Japan.
Shinichiro NakaoDepartment of Emergency and General Medicine, Ikeda City Hospital, Ikeda, Osaka, Japan.
Takato UeokaDepartment of Emergency and General Medicine, Ikeda City Hospital, Ikeda, Osaka, Japan.
Mototoshi ItoDepartment of Emergency and General Medicine, Ikeda City Hospital, Ikeda, Osaka, Japan.
Shinichiro MurakamiDepartment of Emergency and General Medicine, Ikeda City Hospital, Ikeda, Osaka, Japan.
Ikeda Municipal Hospital · JPHannan University · JPThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA total of 105 patients (64 women) who were started on glucocorticoid (GC) treatment for polymyalgia rheumatica (PMR) and/or remitting seronegative symmetrical synovitis with pitting edema (RS

methodsThe GC continuation rate in all patients was examined using the Kaplan-Meier method. The following were compared between the two groups: age at starting GC; sex; erythrocyte sedimentation rate, C-reactive protein, hemoglobin, ferritin, aspartate aminotransferase, and alanine aminotransferase before starting GC; days from the onset of symptoms to GC initiation; GC maximum dose; GC dose half a year after its start; presence of relapse; and existence of concomitant malignant disease.

resultsThe GC continuation rate 7.5 years after GC initiation was 52.5%, higher in women (69.2%), than in men (27.1%). The rates then remained unchanged for 15 years. Hemoglobin was high, and relapse was uncommon in the group that stopped GC. There were no differences in other items.

conclusionIt is difficult to stop GC therapy for PMR in women in Japan, especially in cases with severe anemia.

Indexed as

discontinuation of therapyglucocorticoidpolymyalgia rheumaticaremitting seronegative symmetrical synovitis with pitting edema syndromesex difference

Identifiers

PMID34675610
PMCPMC8502034
OpenAlexW3202817670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.