Evidence map›Paper›PMID 34675594›Full record

ArticleJournal of inflammation research2021

Altered T-Cell Subsets are Associated with Dysregulated Cytokine Secretion of CD4

Di Wang, Yu Jiang, Yangzi Song, Yongqin Zeng, Cuilin Li, Xinyue Wang, Ying Liu, Jiang Xiao, Yaxian Kong, Hongxin Zhao

Open access · goldAbstract read
In one paragraph

Article in Journal of inflammation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Protein-dependent CD4iScience · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Di WangClinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Yu JiangBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Yangzi SongClinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Yongqin ZengClinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Cuilin LiClinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Xinyue WangBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Ying LiuClinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Jiang XiaoClinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Yaxian KongBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Hongxin ZhaoClinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0002-7856-2877
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCD4

methodsA cross-sectional study was performed on 40 healthy controls, 134 ART-naïve PLHIV, and 34 individuals who experienced 3-year ART with low baseline CD4 count from 4 August 2016 to 23 January 2019. We determined the frequencies of CD4

resultsWe found that CD4

conclusionThese data identified the impaired capacity of cytokine secretion in CD4

Indexed as

cytokinesHIV infectioninflammatory responsesT-cell dysfunctionT-cell subsets

Identifiers

PMID34675594
PMCPMC8504938
OpenAlexW3202385514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.