Evidence map›Paper›PMID 34675558›Full record

ArticleInfection and drug resistance2021

Development and Validation of Multiplex Quantitative PCR Assay for Detection of

Hasyanee Binmaeil, Alfizah Hanafiah, Isa Mohamed Rose, Raja Affendi Raja Ali

Erratum issuedAbstract read
In one paragraph

Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Journal of translational autoimmunity · 2026
    Article
  2. Article
  3. Association of Resistance-AssociatedAntibiotics (Basel, Switzerland) · 2026
    Article
  4. Review
  5. International journal of molecular sciences · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Change in Diagnosis ofAntibiotics (Basel, Switzerland) · 2024
    Review
  10. Antibiotic Resistance ofJournal of Korean medical science · 2024
    Review
  11. OptimizingGut and liver · 2023
    Review
  12. Article
  13. Review
  14. Pathogens (Basel, Switzerland) · 2023
    Article
  15. Antibiotic resistance ofFrontiers in cellular and infection microbiology · 2023
    Article
  16. Usefulness of Molecular Methods forInternational journal of molecular sciences · 2022
    Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Hasyanee BinmaeilDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia.ORCID 0000-0002-2129-5800
Alfizah HanafiahDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia.ORCID 0000-0003-4859-1439
Isa Mohamed RoseDepartment of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia.
Raja Affendi Raja AliGUT Research Group, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, 56000, Malaysia.ORCID 0000-0003-4995-3868

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS AND

objectivesMore than half of the world's population is infected with MATERIALS AND

methodsSpecific primers and probes were designed to amplify

resultsIn this study, 14.7% (84/571) of the gastric biopsies were positive for

conclusionThe effectiveness of this qPCR is that it is sensitive in detecting low bacterial load and will help in timely detection of clarithromycin- and levofloxacin-resistant strains, especially in case of mixed infections. Since it is culture independent, it can inform clinicians about antibiotics to be included in the first-line therapy, thereby improving the management of

Indexed as

clarithromycinHelicobacter pylorilevofloxacinmultiplex qPCRmutationresistance

Identifiers

PMID34675558
PMCPMC8502538

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.